Błażej Nowak1, Piotr Szymański2, Igor Pańkowski3, Agnieszka Szarowska4, Katarzyna Życińska5, Wojciech Rogowski6, Robert Gil7, Mariusz Furmanek8, Jacek Tatur9, Artur Zaczyński1, Zbigniew Król10, Waldemar Wierzba11. 1. Clinical Department of Neurosurgery, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 2. Center for Postgraduate Medical Education, Warsaw, Poland; Clinical Department of Interventional Cardiology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland. pszymanski@ptkardio.pl 3. Emergency Department, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 4. Clinical Department of Internal Diseases and Hepatology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 5. Clinical Department of Internal Diseases and Rheumatology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 6. Clinical Department of Urology and Urological Oncology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 7. Center for Postgraduate Medical Education, Warsaw, Poland; Clinical Department of Interventional Cardiology, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 8. Diagnostic Radiology Department, Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 9. Medical University of Warsaw, Warsaw, Poland 10. Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland 11. Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw, Warsaw, Poland; Satellite Campus in Warsaw, University of Humanities and Economics in Lodz, Warsaw, Poland
Abstract
INTRODUCTION: Since the first reported case of coronavirus disease 2019 (COVID‑19) in Poland, the worldwide pandemic has spread throughout the country, leading to many hospital admissions. There has been an urgent need to determine clinical characteristics of Polish patients with laboratory‑confirmed severe acute respiratory syndrome coronavirus 2 (SARS‑CoV 2) infection in the clinical setting. OBJECTIVES: The aim of this retrospective study was to outline characteristics and short‑ term outcomes of SARS‑CoV‑2-positive patients. PATIENTS AND METHODS: We retrospectively assessed 169 consecutive patients with laboratory‑ confirmed COVID‑ 19 with regard to their clinical manifestations, radiological findings, treatment, complications, and outcomes. RESULTS: Of the 169 patients, more than half was aged 65 years or older (88; 52.1%), 51.5% were male, and 78.3% had comorbidities. The majority of patients (106; 62.7%) were transferred from outbreak locations in medical facilities. The most common symptoms on admission were fever (42%), shortness of breath (35%), and fatigue (33%). Twenty seven (15.4%) patients required intensive care unit admission. Overall mortality was 26.3% (n = 46) and was significantly higher in patients transferred from other facilities (38 out of 106; 35.8%), than in patients admitted directly to the hospital (8 out of 63; 12.69%; P <0.001). Seventeen out of 29 patients admitted to the intensive care unit died (mortality, 58.6%), including 30 out of 41 patients with acute respiratory distress syndrome (73.2% mortality rate). CONCLUSIONS: Polish patients with COVID‑19 have similar characteristics and risk factors for adverse outcomes to those observed in countries in which outbreaks occurred earlier. Significantly higher mortality in patients transferred from other centers warrants special attention and transfer policy should be verified.
INTRODUCTION: Since the first reported case of coronavirus disease 2019 (COVID‑19) in Poland, the worldwide pandemic has spread throughout the country, leading to many hospital admissions. There has been an urgent need to determine clinical characteristics of Polish patients with laboratory‑confirmed severe acute respiratory syndrome coronavirus 2 (SARS‑CoV 2) infection in the clinical setting. OBJECTIVES: The aim of this retrospective study was to outline characteristics and short‑ term outcomes of SARS‑CoV‑2-positive patients. PATIENTS AND METHODS: We retrospectively assessed 169 consecutive patients with laboratory‑ confirmed COVID‑ 19 with regard to their clinical manifestations, radiological findings, treatment, complications, and outcomes. RESULTS: Of the 169 patients, more than half was aged 65 years or older (88; 52.1%), 51.5% were male, and 78.3% had comorbidities. The majority of patients (106; 62.7%) were transferred from outbreak locations in medical facilities. The most common symptoms on admission were fever (42%), shortness of breath (35%), and fatigue (33%). Twenty seven (15.4%) patients required intensive care unit admission. Overall mortality was 26.3% (n = 46) and was significantly higher in patients transferred from other facilities (38 out of 106; 35.8%), than in patients admitted directly to the hospital (8 out of 63; 12.69%; P <0.001). Seventeen out of 29 patients admitted to the intensive care unit died (mortality, 58.6%), including 30 out of 41 patients with acute respiratory distress syndrome (73.2% mortality rate). CONCLUSIONS: Polish patients with COVID‑19 have similar characteristics and risk factors for adverse outcomes to those observed in countries in which outbreaks occurred earlier. Significantly higher mortality in patients transferred from other centers warrants special attention and transfer policy should be verified.
Authors: Felix M Reyes; Manuel Hache-Marliere; Dimitris Karamanis; Cesar G Berto; Rodolfo Estrada; Matthew Langston; George Ntaios; Perminder Gulani; Chirag D Shah; Leonidas Palaiodimos Journal: J Clin Med Date: 2021-05-13 Impact factor: 4.241
Authors: Stephan Katzenschlager; Alexandra J Zimmer; Claudius Gottschalk; Jürgen Grafeneder; Stephani Schmitz; Sara Kraker; Marlene Ganslmeier; Amelie Muth; Alexander Seitel; Lena Maier-Hein; Andrea Benedetti; Jan Larmann; Markus A Weigand; Sean McGrath; Claudia M Denkinger Journal: PLoS One Date: 2021-07-29 Impact factor: 3.240
Authors: Stephan Katzenschlager; Alexandra J Zimmer; Claudius Gottschalk; Juergen Grafeneder; Alexander Seitel; Lena Maier-Hein; Andrea Benedetti; Jan Larmann; Markus A Weigand; Sean McGrath; Claudia M Denkinger Journal: medRxiv Date: 2020-11-12
Authors: Edouard L Fu; Roemer J Janse; Ype de Jong; Vera H W van der Endt; Jet Milders; Esmee M van der Willik; Esther N M de Rooij; Olaf M Dekkers; Joris I Rotmans; Merel van Diepen Journal: Clin Kidney J Date: 2020-09-02