Literature DB >> 32419900

Risk factors for excessive tidal volumes delivered during intraoperative mechanical ventilation, a retrospective study.

Chao-Ying Kowa1,2, Zhaosheng Jin1,3, Rebecca Longbottom1, Benjamin Cullinger1, Peter Walker1.   

Abstract

BACKGROUND: Lung Protective Ventilation (LPV) refers to a combination of measures aimed at reducing ventilator-associated lung injury. This includes: delivering tidal volumes of 6-8 ml/kg of ideal body weight, use of positive end expiratory pressure and recruitment maneuvers. With Postoperative Pulmonary Complications (PPCs) contributing towards significant morbidity and mortality following surgery, evidence indicates that effective use of LPV measures intraoperatively has been associated with reduced rates of PPCs.
METHODS: We conducted a post-hoc analysis using data from a recent clinical audit on departmental ventilation practices. Potential risk factors for excessive tidal volume ventilation were assessed using univariable and multivariable regression models.
RESULTS: Obesity and gender are independently associated with risk of excessive ventilation. In contrast, the urgency and length of surgery, the choice of airway devices and the mode of ventilation were not associated with excessive ventilation.
CONCLUSION: There is an association between female gender, obesity and excessive tidal volume ventilation. This may be addressed through formal, protocolized intraoperative ventilation setting. IJPPP
Copyright © 2020.

Entities:  

Keywords:  Intraoperative care; lung diseases; lung protective ventilation; perioperative care; postoperative complications

Year:  2020        PMID: 32419900      PMCID: PMC7218738     

Source DB:  PubMed          Journal:  Int J Physiol Pathophysiol Pharmacol        ISSN: 1944-8171


  26 in total

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1.  Sex Differences in Use of Low Tidal Volume Ventilation in COVID-19-Insights From the PRoVENT-COVID Study.

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