Literature DB >> 32419872

The Charcot Neuroarthropathy as Onset of Type 2 Diabetes - a Diagnostic Challenge.

Alexandru-Madalin Buse1, Doina-Andrada Mihai1, Leonard Lupu1, Teodor Salmen1, Daniela Stegaru1, Gabriela Radulian1.   

Abstract

Introduction: The Charcot neuro-osteoarthropathy is a devastating complication of diabetes, with negative impact on both prognosis and quality of life. Moreover, the diagnostic is often missed or delayed. Case report: A 50 years old male patient with dyslipidemia, overweight and hypertension was referred to our Diabetes Department in the context of newly diagnosed diabetes (HbA1C=11.7%), four days after left hallux trans-metatarsal amputation and debridement of the dorsal collection, for wet gangrene of the left hallux, with dorsal extension. The diagnostic of diabetic neuro-osteoarthropathy of the left foot was delayed several months. A good glycemic control was achieved with insulin glargine and metformin. We look further to introducing modern antidiabetic drugs with not only proven cardiovascular benefit but also good impact on weight. The patient needs to be managed by a multidisciplinary team, which has to include a podiatrist and a vascular surgeon. Conclusions: This case suggest the importance of rising diabetes and diabetic peripheral polyneuropathy awareness in all medical fields.

Entities:  

Year:  2020        PMID: 32419872      PMCID: PMC7221283          DOI: 10.26574/maedica.2020.15.1.122

Source DB:  PubMed          Journal:  Maedica (Bucur)        ISSN: 1841-9038


  13 in total

1.  Off-loading practices for the wounded foot: concepts and choices.

Authors:  Donald E Mrdjenovich
Journal:  J Am Col Certif Wound Spec       Date:  2011-10-03

2.  Prevalence of diabetes mellitus and prediabetes in the adult Romanian population: PREDATORR study.

Authors:  Maria Mota; Simona Georgiana Popa; Eugen Mota; Adina Mitrea; Doina Catrinoiu; Dan Mircea Cheta; Cristian Guja; Nicolae Hancu; Constantin Ionescu-Tirgoviste; Radu Lichiardopol; Bogdan Mircea Mihai; Amorin Remus Popa; Cornelia Zetu; Cornelia Gabriela Bala; Gabriela Roman; Cristian Serafinceanu; Viorel Serban; Romulus Timar; Ioan Andrei Veresiu; Adrian Radu Vlad
Journal:  J Diabetes       Date:  2015-05-06       Impact factor: 4.006

3.  American association of clinical endocrinologists and american college of endocrinology - clinical practice guidelines for developing a diabetes mellitus comprehensive care plan - 2015.

Authors:  Yehuda Handelsman; Zachary T Bloomgarden; George Grunberger; Guillermo Umpierrez; Robert S Zimmerman; Timothy S Bailey; Lawrence Blonde; George A Bray; A Jay Cohen; Samuel Dagogo-Jack; Jaime A Davidson; Daniel Einhorn; Om P Ganda; Alan J Garber; W Timothy Garvey; Robert R Henry; Irl B Hirsch; Edward S Horton; Daniel L Hurley; Paul S Jellinger; Lois Jovanovič; Harold E Lebovitz; Derek LeRoith; Philip Levy; Janet B McGill; Jeffrey I Mechanick; Jorge H Mestman; Etie S Moghissi; Eric A Orzeck; Rachel Pessah-Pollack; Paul D Rosenblit; Aaron I Vinik; Kathleen Wyne; Farhad Zangeneh
Journal:  Endocr Pract       Date:  2015-04       Impact factor: 3.443

4.  Global estimates of undiagnosed diabetes in adults.

Authors:  Jessica Beagley; Leonor Guariguata; Clara Weil; Ayesha A Motala
Journal:  Diabetes Res Clin Pract       Date:  2013-12-01       Impact factor: 5.602

5.  The Charcot foot in diabetes.

Authors:  Lee C Rogers; Robert G Frykberg; David G Armstrong; Andrew J M Boulton; Michael Edmonds; Georges Ha Van; Agnes Hartemann; Frances Game; William Jeffcoate; Alexandra Jirkovska; Edward Jude; Stephan Morbach; William B Morrison; Michael Pinzur; Dario Pitocco; Lee Sanders; Dane K Wukich; Luigi Uccioli
Journal:  Diabetes Care       Date:  2011-09       Impact factor: 19.112

6.  The Effect of Charcot Neuroarthropathy on Limb Preservation in Diabetic Patients with Foot Wound and Critical Limb Ischemia after Balloon Angioplasty.

Authors:  Mehmet Burak Çildağ; Ömer Faruk Kutsi Köseoğlu
Journal:  J Diabetes Res       Date:  2017-08-29       Impact factor: 4.011

7.  Prevalence of Charcot Arthropathy in Type 2 Diabetes Patients Aged over 50 Years with Severe Peripheral Neuropathy: A Retrospective Study in a Tertiary Care South Indian Hospital.

Authors:  Dharmadas Salini; Kumar Harish; Pillay Minnie; Karimassery R Sundaram; Bal Arun; Chirukandath J Sandya; Thacho S Mangalanandan; Lakshmanan Vivek; Valiyaparambil P Praveen
Journal:  Indian J Endocrinol Metab       Date:  2018 Jan-Feb

Review 8.  Initial Diagnosis and Management for Acute Charcot Neuroarthropathy.

Authors:  Matthew L Vopat; Michelle J Nentwig; Alexander C M Chong; Jamie L Agan; Naomi N Shields; Shang-You Yang
Journal:  Kans J Med       Date:  2018-11-29

9.  An overview of the Charcot foot pathophysiology.

Authors:  Gökhan Kaynak; Olgar Birsel; Mehmet Fatih Güven; Tahir Oğüt
Journal:  Diabet Foot Ankle       Date:  2013-08-02

10.  The acute Charcot foot in diabetics: Diagnosis and management.

Authors:  Sohail Yousaf; Edward J C Dawe; Alan Saleh; Ian R Gill; Alex Wee
Journal:  EFORT Open Rev       Date:  2018-10-24
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