Literature DB >> 32419085

Synthesis of new curcumin-based aminocarbonitrile derivatives incorporating 4H-pyran and 1,4-dihydropyridine heterocycles.

Soheila Khajeh Dangolani1, Farhad Panahi2, Ali Khalafi-Nezhad3.   

Abstract

A multicomponent reaction containing curcumin, aldehydes, malononitrile and amine was developed for the one-pot synthesis of a novel library of 4H-pyran and 1,4-dihyropyridin heterocycles incorporating curcumin moiety. The products were obtained in the presence of p-toluenesulfonic acid as catalyst in ethanol as solvent in good to excellent yields.
© 2020. Springer Nature Switzerland AG.

Entities:  

Keywords:  Aminocarbonitriles; Curcumin; Dihydropyridine; Multicomponent reactions; Pyran

Mesh：

Substances：

Year:  2020        PMID： 32419085     DOI： 10.1007/s11030-020-10104-3

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  33 in total

1.  Synthesis of water-soluble curcumin derivatives and their inhibition on lysozyme amyloid fibrillation.

Authors:  Sujuan Wang; Xixi Peng; Liangliang Cui; Tongtong Li; Bei Yu; Gang Ma; Xinwu Ba
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2017-09-08       Impact factor: 4.098

2.  Evaluation of curcumin acetates and amino acid conjugates as proteasome inhibitors.

Authors:  Sheng Biao Wan; Huanjie Yang; Zhongyuan Zhou; Qiuzhi Cindy Cui; Di Chen; Jyoti Kanwar; Imthiyaz Mohammad; Q Ping Dou; Tak Hang Chan
Journal:  Int J Mol Med       Date:  2010-10       Impact factor: 4.101

3.  Activation of anti-oxidant Nrf2 signaling by enone analogues of curcumin.

Authors:  Lorraine M Deck; Lucy A Hunsaker; Thomas A Vander Jagt; Lisa J Whalen; Robert E Royer; David L Vander Jagt
Journal:  Eur J Med Chem       Date:  2017-11-21       Impact factor: 6.514

Review 4.  Pharmacology of Curcuma longa.

Authors:  H P Ammon; M A Wahl
Journal:  Planta Med       Date:  1991-02       Impact factor: 3.352

5.  Antioxidant and anti-inflammatory potential of curcumin accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats.

Authors:  Vinay Kant; Anu Gopal; Nitya N Pathak; Pawan Kumar; Surendra K Tandan; Dinesh Kumar
Journal:  Int Immunopharmacol       Date:  2014-03-24       Impact factor: 4.932

6.  Alpha-glucosidase inhibition of natural curcuminoids and curcumin analogs.

Authors:  Zhi-yun Du; Rong-rong Liu; Wei-yan Shao; Xue-pu Mao; Lin Ma; Lian-quan Gu; Zhi-shu Huang; Albert S C Chan
Journal:  Eur J Med Chem       Date:  2006-01-04       Impact factor: 6.514

7.  Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties.

Authors:  Satyendra Mishra; Upma Narain; Roli Mishra; Krishna Misra
Journal:  Bioorg Med Chem       Date:  2005-03-01       Impact factor: 3.641

8.  Abnormal solvent effects on hydrogen atom abstraction. 2. Resolution of the curcumin antioxidant controversy. The role of sequential proton loss electron transfer.

Authors:  Grzegorz Litwinienko; K U Ingold
Journal:  J Org Chem       Date:  2004-09-03       Impact factor: 4.354

Review 9.  Curcumin as "Curecumin": from kitchen to clinic.

Authors:  Ajay Goel; Ajaikumar B Kunnumakkara; Bharat B Aggarwal
Journal:  Biochem Pharmacol       Date:  2007-08-19       Impact factor: 5.858

10.  Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.

Authors:  R Rashmi; T R Santhosh Kumar; D Karunagaran
Journal:  FEBS Lett       Date:  2003-03-13       Impact factor: 4.124
View more
  1 in total

1.  Chitosan-EDTA-Cellulose network as a green, recyclable and multifunctional biopolymeric organocatalyst for the one-pot synthesis of 2-amino-4H-pyran derivatives.

Authors:  Negin Rostami; Mohammad G Dekamin; Ehsan Valiey; Hamidreza Fanimoghadam
Journal:  Sci Rep       Date:  2022-05-23       Impact factor: 4.996
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.