Literature DB >> 32412805

Promising Immuno-Oncology Options for the Future: Cellular Therapies and Personalized Cancer Vaccines.

Benjamin J Solomon1, Paul A Beavis1, Philip K Darcy1.   

Abstract

A common pathway for an effective immune anticancer response involves recognition of tumor neoantigens and subsequent targeting of cancer cells by T cells. In this article, we provide an overview of the current status of two approaches to directly enhance this interaction using either adoptive cell therapy or personalized cancer vaccines with focus on recent advances in solid tumors, including lung cancer.

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Year:  2020        PMID: 32412805     DOI: 10.1200/EDBK_281101

Source DB:  PubMed          Journal:  Am Soc Clin Oncol Educ Book        ISSN: 1548-8748


  1 in total

1.  NeoScore Integrates Characteristics of the Neoantigen:MHC Class I Interaction and Expression to Accurately Prioritize Immunogenic Neoantigens.

Authors:  Elizabeth S Borden; Suhail Ghafoor; Kenneth H Buetow; Bonnie J LaFleur; Melissa A Wilson; K Taraszka Hastings
Journal:  J Immunol       Date:  2022-03-18       Impact factor: 5.426

  1 in total

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