Literature DB >> 32410387

Guanidiniocarbonyl-Pyrroles (GCP) - 20 Years of the Schmuck Binding Motif.

Michael Giese1, Jochen Niemeyer1, Jens Voskuhl1.   

Abstract

In this Minireview, an overview about the past 20 years of the guanidiniocarbonyl-pyrrole (GCP) binding motif, which was designed, investigated and applied by Prof. Dr. Carsten Schmuck, is presented. Here we highlight the first steps from design and discovery, initial binding studies, applications in material science to advanced biomedical use in protein modulation and delivery of genetic material.
© 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Entities:  

Keywords:  Gels; materials; protein recognition; supramolecular chemistry; transfection

Year:  2020        PMID： 32410387     DOI： 10.1002/cplu.202000142

Source DB:  PubMed          Journal:  Chempluschem        ISSN： 2192-6506            Impact factor:   2.863


  7 in total

Review 1.  Functional Nano-Objects by Electrostatic Self-Assembly: Structure, Switching, and Photocatalysis.

Authors:  Anja Krieger; Alexander Zika; Franziska Gröhn
Journal:  Front Chem       Date:  2022-03-10       Impact factor: 5.221

2.  Evolution of Artificial Arginine Analogues-Fluorescent Guanidiniocarbonyl-Indoles as Efficient Oxo-Anion Binders.

Authors:  Daniel Sebena; Kevin Rudolph; Bibhisan Roy; Christoph Wölper; Till Nitschke; Sarah Lampe; Michael Giese; Jens Voskuhl
Journal:  Molecules       Date:  2022-05-07       Impact factor: 4.927

3.  A Bivalent Supramolecular GCP Ligand Enables Blocking of the Taspase1/Importin α Interaction.

Authors:  Alexander Höing; Alexander Zimmermann; Lisa Moews; Matthias Killa; Marius Heimann; Astrid Hensel; Jens Voskuhl; Shirley K Knauer
Journal:  ChemMedChem       Date:  2021-10-19       Impact factor: 3.540

4.  Supramolecular polymers with reversed viscosity/temperature profile for application in motor oils.

Authors:  Jan-Erik Ostwaldt; Christoph Hirschhäuser; Stefan K Maier; Carsten Schmuck; Jochen Niemeyer
Journal:  Beilstein J Org Chem       Date:  2021-01-12       Impact factor: 2.883

5.  A tribute to Carsten Schmuck.

Authors:  Jochen Niemeyer; Ivo Piantanida; Thomas Schrader
Journal:  Beilstein J Org Chem       Date:  2021-11-29       Impact factor: 2.883

6.  Advances towards Cell-Specific Gene Transfection: A Small-Molecule Approach Allows Order-of-Magnitude Selectivity.

Authors:  Thies Dirksmeyer; Paul Stahl; Cecilia Vallet; Shirley Knauer; Michael Giese; Carsten Schmuck; Christoph Hirschhäuser
Journal:  Chemistry       Date:  2022-06-17       Impact factor: 5.020

7.  Computational model predicts protein binding sites of a luminescent ligand equipped with guanidiniocarbonyl-pyrrole groups.

Authors:  Neda Rafieiolhosseini; Matthias Killa; Thorben Neumann; Niklas Tötsch; Jean-Noël Grad; Alexander Höing; Thies Dirksmeyer; Jochen Niemeyer; Christian Ottmann; Shirley K Knauer; Michael Giese; Jens Voskuhl; Daniel Hoffmann
Journal:  Beilstein J Org Chem       Date:  2022-09-23       Impact factor: 2.544
  7 in total

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