Literature DB >> 32409435

Coagulopathy in COVID-19: Manifestations and management.

Simon R Mucha1,2, Siddharth Dugar3,4, Keith McCrae5,6, Douglas Joseph7,8, John Bartholomew9,10, Gretchen L Sacha11, Michael Militello11.   

Abstract

Severe COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19- associated coagulopathy. Prophylaxis against venous thromboembolism is paramount for all hospitalized patients, with more aggressive prophylaxis and screening recommended for patients with D-dimer levels above 3.0 μg/mL. Point-of-care ultrasonography is the imaging method of choice for patients at high risk, as it entails minimal risk of exposing providers to the virus.
Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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Year:  2020        PMID: 32409435     DOI: 10.3949/ccjm.87a.ccc024

Source DB:  PubMed          Journal:  Cleve Clin J Med        ISSN: 0891-1150            Impact factor:   2.321


  23 in total

1.  Thromboprophylaxis with enoxaparin is associated with a lower death rate in patients hospitalized with SARS-CoV-2 infection. A cohort study.

Authors:  Filippo Albani; Lilia Sepe; Federica Fusina; Chiara Prezioso; Manuela Baronio; Federica Caminiti; Antonella Di Maio; Barbara Faggian; Maria Elena Franceschetti; Marco Massari; Marcello Salvaggio; Giuseppe Natalini
Journal:  EClinicalMedicine       Date:  2020-10-05

2.  Prevalence of Pulmonary Embolism in COVID-19: a Pooled Analysis.

Authors:  Rupak Desai; Zainab Gandhi; Sandeep Singh; Sonali Sachdeva; Pritika Manaktala; Sejal Savani; Virmitra Desai; Rajesh Sachdeva; Gautam Kumar
Journal:  SN Compr Clin Med       Date:  2020-10-28

3.  Serial markers of coagulation and inflammation and the occurrence of clinical pulmonary thromboembolism in mechanically ventilated patients with SARS-CoV-2 infection; the prospective Maastricht intensive care COVID cohort.

Authors:  Mark M G Mulder; LIoyd Brandts; Renée A G Brüggemann; Marcel Koelmann; Alexander S Streng; Renske H Olie; Hester A Gietema; Henri M H Spronk; Iwan C C van der Horst; Jan-Willem E M Sels; Joachim E Wildberger; Sander M J van Kuijk; Ronny M Schnabel; Hugo Ten Cate; Yvonne M C Henskens; Bas C T van Bussel
Journal:  Thromb J       Date:  2021-05-31

4.  The Spectrum of Gastrointestinal Symptoms in Patients With Coronavirus Disease-19: Predictors, Relationship With Disease Severity, and Outcome.

Authors:  Uday C Ghoshal; Ujjala Ghoshal; Akash Mathur; Ratender K Singh; Alok Nath; Atul Garg; Dharamveer Singh; Sanjay Singh; Jasmeet Singh; Ankita Pandey; Sushmita Rai; Shruthi Vasanth; Radha Krishan Dhiman
Journal:  Clin Transl Gastroenterol       Date:  2020-12       Impact factor: 4.396

Review 5.  D-Dimer, Fibrinogen, and IL-6 in COVID-19 Patients with Suspected Venous Thromboembolism: A Narrative Review.

Authors:  Islam Eljilany; Abdel-Naser Elzouki
Journal:  Vasc Health Risk Manag       Date:  2020-11-13

Review 6.  Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes.

Authors:  Corlia Grobler; Siphosethu C Maphumulo; L Mireille Grobbelaar; Jhade C Bredenkamp; Gert J Laubscher; Petrus J Lourens; Janami Steenkamp; Douglas B Kell; Etheresia Pretorius
Journal:  Int J Mol Sci       Date:  2020-07-21       Impact factor: 5.923

7.  [Mortality of covid-19 patients with vascular thrombotic complications].

Authors:  José A Gonzalez-Fajardo; Marina Ansuategui; Carmen Romero; Alejandra Comanges; Diego Gómez-Arbeláez; Gabriela Ibarra; Ania Garcia-Gutierrez
Journal:  Med Clin (Barc)       Date:  2020-11-06       Impact factor: 1.725

8.  Determinants of Increased Fibrinogen in COVID-19 Patients With and Without Diabetes and Impaired Fasting Glucose.

Authors:  Zhenzhou Wang; Zhe Du; Xiujuan Zhao; Fuzheng Guo; Tianbing Wang; Fengxue Zhu
Journal:  Clin Appl Thromb Hemost       Date:  2021 Jan-Dec       Impact factor: 2.389

Review 9.  A clinical primer for the expected and potential post-COVID-19 syndromes.

Authors:  Brian Walitt; Elizabeth Bartrum
Journal:  Pain Rep       Date:  2021-02-16

10.  Penile Mondor's in a Covid-19 patient on prophylactic anti-thrombosis with rivaroxaban: a case report.

Authors:  Murat Tuğrul Eren; Hakan Özveri; Hilal Kurtoğlu
Journal:  Afr J Urol       Date:  2021-07-06
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