Literature DB >> 3240908

Isolation and study of fosfomycin-resistant mutants of group A and B streptococci.

L E Ravdonikas1, K B Grabovskaya, A A Totolian.   

Abstract

Eighty-nine fosfomycin-resistant mutants of group A and B streptococci were isolated. The mutants differed essentially from the parent strains in cell-wall characteristics, such as morphology of cocci and chains, sensitivity to detergents and hydrophobic properties. At the same time, the recipient activity of the investigated mutants was not changed. It is supposed that resistance of mutants to fosfomycin is connected with a transport block of glycerol 3-phosphate--important lipoteichoic acid (LTA) structural component. Fosr mutants can be useful for experimental examination of Beachey's hypothesis about the importance of LTA or its complex with the M protein for adhesion.

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Year:  1988        PMID: 3240908     DOI: 10.1007/bf02925778

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN: 0015-5632            Impact factor:   2.099


  13 in total

1.  Chromosomal localization of resistance to fosfomycin and aminocyclitol antibiotics in hospital strains of Staphylococcus aureus.

Authors:  A Młynarczyk; G Młynarczyk; J Bardowski; H Osowiecki
Journal:  Acta Microbiol Pol       Date:  1985

Review 2.  Mutagenic clastogenic and oncogenic effects of 1-beta-D-arabinofuranosylcytosine.

Authors:  W F Benedict; P A Jones
Journal:  Mutat Res       Date:  1979-03       Impact factor: 2.433

3.  Isolation and characterization of a phosphonomycin-resistant mutant of Escherichia coli K-12.

Authors:  P S Venkateswaran; H C Wu
Journal:  J Bacteriol       Date:  1972-06       Impact factor: 3.490

4.  An M-associated protein antigen (MAP) of group A streptococci.

Authors:  J P Widdowson; W R Maxted; A M Pinney
Journal:  J Hyg (Lond)       Date:  1971-12

5.  The genetic control of virulence in group A streptococci. III. Plasmid-induced "switch-off"--effect on some pathogenic properties.

Authors:  L E Ravdonikas; P Christensen; L A Burova; K Grabovskaya; L Björck; C Schalen; M L Svensson; A A Totolian
Journal:  Acta Pathol Microbiol Immunol Scand B       Date:  1984-02

6.  Isolation and characterization of Streptococcus mutans mutants defective in adherence and aggregation.

Authors:  H Murchison; S Larrimore; R Curtiss
Journal:  Infect Immun       Date:  1981-12       Impact factor: 3.441

7.  The biochemical mechanisms of resistance by streptococci to the antibiotics D-cycloserine and O-carbamyl-D-serine.

Authors:  R H Reitz; H D Slade; F C Neuhaus
Journal:  Biochemistry       Date:  1967-08       Impact factor: 3.162

8.  Genetic analysis of antibiotic resistance in Streptococcus pyogenes.

Authors:  J G Stuart; J J Ferretti
Journal:  J Bacteriol       Date:  1978-02       Impact factor: 3.490

9.  The genetic control of virulence in group A streptococci. I. Conjugal transfer of plasmids and their effect on expression of some host cell properties.

Authors:  L E Ravdonikas
Journal:  Acta Pathol Microbiol Immunol Scand B       Date:  1983-02

10.  Formation of molecular complexes between a structurally defined M protein and acylated or deacylated lipoteichoic acid of Streptococcus pyogenes.

Authors:  I Ofek; W A Simpson; E H Beachey
Journal:  J Bacteriol       Date:  1982-02       Impact factor: 3.490

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  2 in total

1.  Adherence to epithelial cells and ultrastructure of fosfomycin-resistant mutants of group A streptococci.

Authors:  L E Ravdonikas; M Rýc; K B Grabovskaya; A A Totolian
Journal:  Folia Microbiol (Praha)       Date:  1988       Impact factor: 2.099

Review 2.  Fosfomycin: Uses and potentialities in veterinary medicine.

Authors:  D S Pérez; M O Tapia; A L Soraci
Journal:  Open Vet J       Date:  2014-03-16
  2 in total

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