Literature DB >> 3240763

N1-glucosides as urinary metabolites of sulphadimidine, sulphamerazine and sulphamethoxazole.

B Ahmad1, J W Powell.   

Abstract

The synthesis and characterisation of the N1-beta-D-glucosides of the three title sulphonamides are described, and these conjugates are shown, by means of HPLC and MS, to be minor urinary metabolites of these drugs.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3240763     DOI： 10.1007/BF03189937

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


  9 in total

1.  High-pressure liquid chromatographic separation, identification, and determination of sulfa drugs and their metabolites in urine.

Authors:  J P Sharma; E G Perkins; R F Bevill
Journal:  J Pharm Sci       Date:  1976-11       Impact factor: 3.534

2.  Determination of pharmacokinetic parameters for urinary excretion of sulphafurazole under normal and controlled alkaline urine conditions.

Authors:  A P Goossens; M C Van Oudtshoorn
Journal:  J Pharm Pharmacol       Date:  1970-03       Impact factor: 3.765

3.  Determination of pharmacokinetic parameters for rapid and slow acetylators of sulphadimidine.

Authors:  M C Van Oudtshoorn; F J Potgieter
Journal:  J Pharm Pharmacol       Date:  1972-05       Impact factor: 3.765

4.  The actylation of sulamethazine and sulfamethoxypyridazine by human subjects.

Authors:  T A White; D A Evans
Journal:  Clin Pharmacol Ther       Date:  1968 Jan-Feb       Impact factor: 6.875

5.  Metabolism and disposition by the rat of 35S-sulfadiazine alone and in the presence of trimethoprim.

Authors:  J L Woolley; C W Sigel
Journal:  Drug Metab Dispos       Date:  1979 Mar-Apr       Impact factor: 3.922

6.  The structure of the glucuronide of sulphadimethoxine formed in man.

Authors:  J W Bridges; M R Kibby; R T Williams
Journal:  Biochem J       Date:  1965-09       Impact factor: 3.857

7.  The metabolism of four sulphonamides in cows.

Authors:  P Nielsen
Journal:  Biochem J       Date:  1973-12       Impact factor: 3.857

8.  Simultaneous determination of trimethoprim, sulphamethoxazole and N4-acetylsulphamethoxazole in serum and urine by high-performance liquid chromatography.

Authors:  R Gochin; I Kanfer; J M Haigh
Journal:  J Chromatogr       Date:  1981-04-10

9.  Metabolic fate of phenobarbital in man. N-Glucoside formation.

Authors:  B K Tang; W Kalow; A A Grey
Journal:  Drug Metab Dispos       Date:  1979 Sep-Oct       Impact factor: 3.922
  9 in total
  1 in total

1.  Pharmacokinetics, N1-glucuronidation and N4-acetylation of sulfadimethoxine in man.

Authors:  T B Vree; E W Beneken Kolmer; M Martea; R Bosch; Y A Hekster; M Shimoda
Journal:  Pharm Weekbl Sci       Date:  1990-04-27
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.