Literature DB >> 3240565

Assay of cardiolipin peroxidation by high-performance liquid chromatography.

N L Parinandi1, B K Weis, H H Schmid.   

Abstract

Commercial preparations of bovine cardiolipin (diphosphatidylglycerol) in chloroform solution contain substantial amounts of oxidation products. These oxidized derivatives, characterized by the presence of varying amounts of hydroperoxides and conjugated dienes, can be separated from unoxidized cardiolipin by normal phase high-performance liquid chromatography (HPLC) using UV detection. When purified cardiolipin is subjected to autoxidation in aqueous media, oxidation products of similar HPLC properties are produced. Storage of cardiolipin in chloroform induces both autoxidation and hydrolysis whereas storage in ethanol and other solvents does not. It is recommended not to use chloroform for the long-term storage of cardiolipin.

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Year:  1988        PMID： 3240565     DOI： 10.1016/0009-3084(88)90009-6

Source DB:  PubMed          Journal:  Chem Phys Lipids        ISSN： 0009-3084            Impact factor:   3.329


  7 in total

1.  Cytochrome c release from mitochondria proceeds by a two-step process.

Authors:  Martin Ott; John D Robertson; Vladimir Gogvadze; Boris Zhivotovsky; Sten Orrenius
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-29       Impact factor: 11.205

2.  Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis.

Authors:  K Nomura; H Imai; T Koumura; T Kobayashi; Y Nakagawa
Journal:  Biochem J       Date:  2000-10-01       Impact factor: 3.857

3.  Elucidating the mechanism of ferrocytochrome c heme disruption by peroxidized cardiolipin.

Authors:  Andrej Musatov; Marian Fabian; Rastislav Varhač
Journal:  J Biol Inorg Chem       Date:  2012-11-18       Impact factor: 3.358

4.  Relationship between lipid saturation and lipid-protein interaction in liver mitochondria modified by catalytic hydrogenation with reference to cardiolipin molecular species.

Authors:  M Schlame; L Horvàth; L Vìgh
Journal:  Biochem J       Date:  1990-01-01       Impact factor: 3.857

5.  A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani.

Authors:  Gaurav Gupta; Kevin J Peine; Dalia Abdelhamid; Heidi Snider; Andrew B Shelton; Latha Rao; Sainath R Kotha; Andrew C Huntsman; Sanjay Varikuti; Steve Oghumu; C Benjamin Naman; Li Pan; Narasimham L Parinandi; Tracy L Papenfuss; A Douglas Kinghorn; Eric M Bachelder; Kristy M Ainslie; James R Fuchs; Abhay R Satoskar
Journal:  ACS Infect Dis       Date:  2015-09-21       Impact factor: 5.084

Review 6.  Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria.

Authors:  Mandip Joshi; Sainath R Kotha; Smitha Malireddy; Vaithinathan Selvaraju; Abhay R Satoskar; Alexender Palesty; David W McFadden; Narasimham L Parinandi; Nilanjana Maulik
Journal:  Mol Cell Biochem       Date:  2013-12-04       Impact factor: 3.396

7.  Dual effect of heparin on Fe²⁺-induced cardiolipin peroxidation: implications for peroxidation of cytochrome c oxidase bound cardiolipin.

Authors:  Andrej Musatov
Journal:  J Biol Inorg Chem       Date:  2013-07-11       Impact factor: 3.358
  7 in total

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