Literature DB >> 32386754

Significant reduction of postoperative pain and opioid analgesics requirement with an Enhanced Recovery After Thoracic Surgery protocol.

Syed S Razi1, Joy A Stephens-McDonnough1, Safi Haq1, Michael Fabbro2, Aliercy Nunez Sanchez3, Richard H Epstein2, Nestor R Villamizar1, Dao M Nguyen4.   

Abstract

OBJECTIVE: To evaluate differences in postoperative pain control and opioids requirement in thoracic surgical patients following implementation of an Enhanced Recovery after Thoracic Surgery protocol with a comprehensive postoperative pain management strategy.
MATERIAL AND METHODS: A retrospective analysis of a prospectively maintained database of patients undergoing pulmonary resections by robotic thoracoscopy or thoracotomy from January 1, 2017, to January 31, 2019, was conducted. Multimodal pain management strategy (opioid-sparing analgesics, infiltration of liposomal bupivacaine to intercostal spaces and surgical sites, and elimination of thoracic epidural analgesia use in thoracotomy patients) was implemented as part of Enhanced Recovery after Thoracic Surgery on February 1, 2018. Outcome metrics including patient-reported pain levels, in-hospital and postdischarge opioids use, postoperative complications, and length of stay were compared before and after protocol implementation.
RESULTS: In total, 310 robotic thoracoscopy and 62 thoracotomy patients met the inclusion criteria. This pain management strategy was associated with significant reduction of postoperative pain in both groups with an overall reduction of postoperative opioids requirement. Median in-hospital opioids use (morphine milligram equivalent per day) was reduced from 30 to 18.36 (P = .009) for the robotic thoracoscopy group and slightly increased from 15.48 to 21.0 (P = .27) in the thoracotomy group. More importantly, median postdischarge opioids prescribed (total morphine milligram equivalent) was significantly reduced from 480.0 to 150.0 (P < .001) and 887.5 to 150.0 (P < .001) for the thoracoscopy and thoracotomy groups, respectively. Similar short-term perioperative outcomes were observed in both groups before and following protocol implementation.
CONCLUSIONS: Implementation of Enhanced Recovery after Thoracic Surgery allows safe elimination of epidural use, better pain control, and less postoperative opioids use, especially a drastic reduction of postdischarge opioid need, without adversely affecting outcomes.
Copyright © 2020 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  ERATS; postoperative pain management

Year:  2020        PMID: 32386754     DOI: 10.1016/j.jtcvs.2019.12.137

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  8 in total

1.  The power of the liposome.

Authors:  Brian N Arnold; Mara B Antonoff
Journal:  JTCVS Open       Date:  2021-06-17

2.  Implementation of an enhanced recovery after thoracic surgery care pathway for thoracotomy patients-achieving better pain control with less (schedule II) opioid utilization.

Authors:  Karishma Kodia; Joy A Stephens-McDonnough; Ahmed Alnajar; Nestor R Villamizar; Dao M Nguyen
Journal:  J Thorac Dis       Date:  2021-07       Impact factor: 2.895

Review 3.  Reducing New Persistent Opioid Use After Surgery: A Review of Interventions.

Authors:  Stacey Burns; Richard Urman; Rachel Pian; Oscar Jim Michael Coppes
Journal:  Curr Pain Headache Rep       Date:  2021-03-24

4.  Potential Impact of Local Anesthetics Inducing Granulocyte Arrest and Altering Immune Functions on Perioperative Outcome.

Authors:  Gesche Kolle; Thomas Metterlein; Michael Gruber; Timo Seyfried; Walter Petermichl; Sophie-Marie Pfaehler; Diane Bitzinger; Sigrid Wittmann; Andre Bredthauer
Journal:  J Inflamm Res       Date:  2021-01-06

5.  Application of Rapid Rehabilitation Nursing in Thoracic Surgery Nursing.

Authors:  Hongliu Liang; Jing Huang; Jijia Tong; Jinyue Wang
Journal:  J Healthc Eng       Date:  2021-09-02       Impact factor: 2.682

6.  Optimization of an Enhanced Recovery After Surgery protocol for opioid-free pain management following robotic thoracic surgery.

Authors:  Karishma Kodia; Ahmed Alnajar; Joanne Szewczyk; Joy Stephens-McDonnough; Nestor R Villamizar; Dao M Nguyen
Journal:  JTCVS Open       Date:  2022-01-25

7.  Enhanced recovery after thoracic surgery: Systematic review and meta-analysis.

Authors:  Audrey L Khoury; Katharine L McGinigle; Nikki L Freeman; Helal El-Zaatari; Cynthia Feltner; Jason M Long
Journal:  JTCVS Open       Date:  2021-07-15

8.  Commentary: Semper ad meliora: Continuous improvement in enhanced recovery pathways.

Authors:  Aaron M Delman; Robert M Van Haren
Journal:  JTCVS Open       Date:  2022-01-19
  8 in total

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