Literature DB >> 32385742

Synthesis of polycyclic N-heterocyclic compounds via one-pot three-component cyclization strategy.

Abdolali Alizadeh1, Elham Sanjari2, Atefeh Roosta2, Mohammad Reza Halvagar3.   

Abstract

Reported herein is an unprecedented and sequential three-component synthetic strategy for the preparation of polycyclic N-heterocyclic compounds. This synthetic protocol enabled the preparation of a series of novel nitrogen-containing pentacyclic compound under convenient conditions in excellent yields and short reaction time. The synthesized products were characterized by IR, 1H NMR, 13C NMR and mass spectra. Furthermore, the definitive structure of target compounds was confirmed by X-ray analysis.
© 2020. Springer Nature Switzerland AG.

Entities:  

Keywords:  Aryl isothiocyanate; Ninhydrin; Polycyclic N-heterocycles; o-Phenylenediamine

Mesh:

Substances:

Year:  2020        PMID: 32385742     DOI: 10.1007/s11030-020-10097-z

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  6 in total

1.  Skeletal diverse synthesis of N-fused polycyclic heterocycles via the sequence of Ugi-type MCR and CuI-catalyzed coupling/tandem Pictet-Spengler reaction.

Authors:  Vikas Tyagi; Shahnawaz Khan; Vikas Bajpai; Harsh M Gauniyal; Brijesh Kumar; Prem M S Chauhan
Journal:  J Org Chem       Date:  2012-01-24       Impact factor: 4.354

2.  Immobilization of N-Heterocyclic Carbene Compounds: A Synthetic Perspective.

Authors:  Rui Zhong; Anja C Lindhorst; Florian J Groche; Fritz E Kühn
Journal:  Chem Rev       Date:  2017-01-13       Impact factor: 60.622

3.  Exploratory Investigations Probing a Preparatively Versatile, Pyridinium Salt Photoelectrocyclization-Solvolytic Aziridine Ring Opening Sequence.

Authors:  Rong Ling; Mutsuo Yoshida; Patrick S. Mariano
Journal:  J Org Chem       Date:  1996-06-26       Impact factor: 4.354

4.  New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides.

Authors:  Kamelia M Amin; Magda M F Ismail; Eman Noaman; Dalia H Soliman; Yousry A Ammar
Journal:  Bioorg Med Chem       Date:  2006-07-14       Impact factor: 3.641

5.  Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication.

Authors:  J P Kleim; R Bender; U M Billhardt; C Meichsner; G Riess; M Rösner; I Winkler; A Paessens
Journal:  Antimicrob Agents Chemother       Date:  1993-08       Impact factor: 5.191

6.  A General Approach to Sequence-Controlled Polymers Using Macrocyclic Ring Opening Metathesis Polymerization.

Authors:  Will R Gutekunst; Craig J Hawker
Journal:  J Am Chem Soc       Date:  2015-06-23       Impact factor: 15.419

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.