Fei Xiong1, Hui Tang2, Li Liu3, Can Tu1, Jian-Bo Tian3, Chun-Tao Lei2, Jing Liu2, Jun-Wu Dong4, Wen-Li Chen5, Xiao-Hui Wang6, Dan Luo7, Ming Shi8, Xiao-Ping Miao3, Chun Zhang9. 1. Department of Nephrology, Wuhan No. 1 Hospital, Wuhan, China. 2. Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 3. Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 4. Department of Nephrology, Wuhan Fourth Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 5. Department of Nephrology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. 6. Department of Nephrology, Wuhan No. 5 Hospital, Wuhan, China. 7. Department of Nephrology, Wuhan Third Hospital, Wuhan, China. 8. Department of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China. 9. Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China drzhangchun@hust.edu.cn.
Abstract
BACKGROUND: Reports indicate that those most vulnerable to developing severe coronavirus disease 2019 (COVID-19) are older adults and those with underlying illnesses, such as diabetes mellitus, hypertension, or cardiovascular disease, which are common comorbidities among patients undergoing maintenance hemodialysis. However, there is limited information about the clinical characteristics of hemodialysis patients with COVID-19 or about interventions to control COVID-19 in hemodialysis centers. METHODS: We collected data retrospectively through an online registration system that includes all patients receiving maintenance hemodialysis at 65 centers in Wuhan, China. We reviewed epidemiologic and clinical data of patients with laboratory-confirmed COVID-19 between January 1, 2020 and March 10, 2020. RESULTS: Of 7154 patients undergoing hemodialysis, 154 had laboratory-confirmed COVID-19. The mean age of the 131 patients in our analysis was 63.2 years; 57.3% were men. Many had underlying comorbidities, with cardiovascular disease (including hypertension) being the most common (68.7%). Only 51.9% of patients manifested fever; 21.4% of infected patients were asymptomatic. The most common finding on chest computed tomography (CT) was ground-grass or patchy opacity (82.1%). After initiating comprehensive interventions-including entrance screening of body temperature and symptoms, universal chest CT and blood tests, and other measures-new patients presenting with COVID-19 peaked at 10 per day on January 30, decreasing to 4 per day on February 11. No new cases occurred between February 26 and March 10, 2020. CONCLUSIONS: We found that patients receiving maintenance hemodialysis were susceptible to COVID-19 and that hemodialysis centers were high-risk settings during the epidemic. Increasing prevention efforts, instituting universal screening, and isolating patients with COVID-19 and directing them to designated hemodialysis centers were effective in preventing the spread of COVID-19 in hemodialysis centers.
BACKGROUND: Reports indicate that those most vulnerable to developing severe coronavirus disease 2019 (COVID-19) are older adults and those with underlying illnesses, such as diabetes mellitus, hypertension, or cardiovascular disease, which are common comorbidities among patients undergoing maintenance hemodialysis. However, there is limited information about the clinical characteristics of hemodialysis patients with COVID-19 or about interventions to control COVID-19 in hemodialysis centers. METHODS: We collected data retrospectively through an online registration system that includes all patients receiving maintenance hemodialysis at 65 centers in Wuhan, China. We reviewed epidemiologic and clinical data of patients with laboratory-confirmed COVID-19 between January 1, 2020 and March 10, 2020. RESULTS: Of 7154 patients undergoing hemodialysis, 154 had laboratory-confirmed COVID-19. The mean age of the 131 patients in our analysis was 63.2 years; 57.3% were men. Many had underlying comorbidities, with cardiovascular disease (including hypertension) being the most common (68.7%). Only 51.9% of patients manifested fever; 21.4% of infectedpatients were asymptomatic. The most common finding on chest computed tomography (CT) was ground-grass or patchy opacity (82.1%). After initiating comprehensive interventions-including entrance screening of body temperature and symptoms, universal chest CT and blood tests, and other measures-new patients presenting with COVID-19 peaked at 10 per day on January 30, decreasing to 4 per day on February 11. No new cases occurred between February 26 and March 10, 2020. CONCLUSIONS: We found that patients receiving maintenance hemodialysis were susceptible to COVID-19 and that hemodialysis centers were high-risk settings during the epidemic. Increasing prevention efforts, instituting universal screening, and isolating patients with COVID-19 and directing them to designated hemodialysis centers were effective in preventing the spread of COVID-19 in hemodialysis centers.
Authors: Ping-Nam Wong; Siu-Ka Mak; Kin-Yee Lo; Gensy M W Tong; Yuk Wong; Chi-Leung Watt; Andrew K M Wong Journal: Am J Kidney Dis Date: 2003-11 Impact factor: 8.860
Authors: Lili Chan; Suraj K Jaladanki; Sulaiman Somani; Ishan Paranjpe; Arvind Kumar; Shan Zhao; Lewis Kaufman; Staci Leisman; Shuchita Sharma; John Cijiang He; Barbara Murphy; Zahi A Fayad; Matthew A Levin; Erwin P Bottinger; Alexander W Charney; Benjamin S Glicksberg; Steven G Coca; Girish N Nadkarni Journal: Clin J Am Soc Nephrol Date: 2020-10-30 Impact factor: 8.237
Authors: Bruce M Robinson; Murilo Guedes; Mohammed Alghonaim; Aleix Cases; Indranil Dasgupta; Liangying Gan; Stefan H Jacobson; Talerngsak Kanjanabuch; Yong-Lim Kim; Werner Kleophas; Laura Labriola; Rachel L Perlman; Gianpaolo Reboldi; Vesh Srivatana; Rita S Suri; Kazuhiko Tsuruya; Pablo Urena Torres; Ronald L Pisoni; Roberto Pecoits-Filho Journal: Kidney Med Date: 2021-05-14
Authors: Johan De Meester; Dirk De Bacquer; Maarten Naesens; Bjorn Meijers; Marie M Couttenye; An S De Vriese Journal: J Am Soc Nephrol Date: 2020-11-05 Impact factor: 10.121
Authors: Francesco Giovinazzo; Alfonso W Avolio; Federica Galiandro; Alessandro Vitale; Giulio V Dalla Riva; Gianni Biancofiore; Shivani Sharma; Paolo Muiesan; Salvatore Agnes; Patrizia Burra Journal: Transplant Direct Date: 2021-02-11