Literature DB >> 32380492

Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions.

Jan Schuemann1, Alexander F Bagley, Ross Berbeco, Kyle Bromma, Karl T Butterworth, Hilary L Byrne, B Devika Chithrani, Sang Hyun Cho, Jason R Cook, Vincent Favaudon, Yaser H Gholami, Elisabetta Gargioni, James F Hainfeld, Félicien Hespeels, Anne-Catherine Heuskin, Udoka M Ibeh, Zdenka Kuncic, Sijumon Kunjachan, Sandrine Lacombe, Stéphane Lucas, François Lux, Stephen McMahon, Dmitry Nevozhay, Wilfred Ngwa, J Donald Payne, Sébastien Penninckx, Erika Porcel, Kevin M Prise, Hans Rabus, Sharif M Ridwan, Benedikt Rudek, Léon Sanche, Bijay Singh, Henry M Smilowitz, Konstantin V Sokolov, Srinivas Sridhar, Yaroslav Stanishevskiy, Wonmo Sung, Olivier Tillement, Needa Virani, Wassana Yantasee, Sunil Krishnan.   

Abstract

This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z = 22, to Bismuth, Z = 83) and a similarly wide spectrum of potential clinical applications, including diagnostic, therapeutic (radiation dose enhancers, hyperthermia inducers, drug delivery vehicles, vaccine adjuvants, photosensitizers, enhancers of immunotherapy) and theranostic (combining both diagnostic and therapeutic), are being fabricated and evaluated. This roadmap covers contributions from experts in these topics summarizing their view of the current status and challenges, as well as expected advancements in technology to address these challenges.

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Year:  2020        PMID: 32380492     DOI: 10.1088/1361-6560/ab9159

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  26 in total

Review 1.  A Critical Review of Radiation Therapy: From Particle Beam Therapy (Proton, Carbon, and BNCT) to Beyond.

Authors:  Yoshitaka Matsumoto; Nobuyoshi Fukumitsu; Hitoshi Ishikawa; Kei Nakai; Hideyuki Sakurai
Journal:  J Pers Med       Date:  2021-08-23

2.  Bias-voltage dependent operational characteristics of a fully spectroscopic pixelated cadmium telluride detector system within an experimental benchtop x-ray fluorescence imaging setup.

Authors:  Hem Moktan; Raj Kumar Panta; Sang Hyun Cho
Journal:  Biomed Phys Eng Express       Date:  2021-12-07

Review 3.  Gold Nanoparticles as a Potent Radiosensitizer: A Transdisciplinary Approach from Physics to Patient.

Authors:  Sébastien Penninckx; Anne-Catherine Heuskin; Carine Michiels; Stéphane Lucas
Journal:  Cancers (Basel)       Date:  2020-07-23       Impact factor: 6.639

Review 4.  Carbon Ion Radiobiology.

Authors:  Walter Tinganelli; Marco Durante
Journal:  Cancers (Basel)       Date:  2020-10-17       Impact factor: 6.575

5.  Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques.

Authors:  Lawrence Bronk; Fada Guan; Darshana Patel; Duo Ma; Benjamin Kroger; Xiaochun Wang; Kevin Tran; Joycelyn Yiu; Clifford Stephan; Jürgen Debus; Amir Abdollahi; Oliver Jäkel; Radhe Mohan; Uwe Titt; David R Grosshans
Journal:  Cancers (Basel)       Date:  2020-12-05       Impact factor: 6.639

Review 6.  Radiation nanosensitizers in cancer therapy-From preclinical discoveries to the outcomes of early clinical trials.

Authors:  Colette Bilynsky; Nadine Millot; Anne-Laure Papa
Journal:  Bioeng Transl Med       Date:  2021-09-23

7.  Three-Dimensional Tumor Spheroids as a Tool for Reliable Investigation of Combined Gold Nanoparticle and Docetaxel Treatment.

Authors:  Kyle Bromma; Abdulaziz Alhussan; Monica Mesa Perez; Perry Howard; Wayne Beckham; Devika B Chithrani
Journal:  Cancers (Basel)       Date:  2021-03-23       Impact factor: 6.639

8.  Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment.

Authors:  Abdulaziz Alhussan; Kyle Bromma; Ece Pinar Demirci Bozdoğan; Andrew Metcalfe; Joanna Karasinska; Wayne Beckham; Abraham S Alexander; Daniel J Renouf; David F Schaeffer; Devika B Chithrani
Journal:  Curr Oncol       Date:  2021-05-24       Impact factor: 3.677

9.  Impact of superparamagnetic iron oxide nanoparticles on in vitro and in vivo radiosensitisation of cancer cells.

Authors:  Emily Russell; Victoria Dunne; Ben Russell; Hibaaq Mohamud; Mihaela Ghita; Stephen J McMahon; Karl T Butterworth; Giuseppe Schettino; Conor K McGarry; Kevin M Prise
Journal:  Radiat Oncol       Date:  2021-06-12       Impact factor: 3.481

10.  Combining Augmented Radiotherapy and Immunotherapy through a Nano-Gold and Bacterial Outer-Membrane Vesicle Complex for the Treatment of Glioblastoma.

Authors:  Mei-Hsiu Chen; Tse-Ying Liu; Yu-Chiao Chen; Ming-Hong Chen
Journal:  Nanomaterials (Basel)       Date:  2021-06-24       Impact factor: 5.076

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