Literature DB >> 32379351

Blood microparticles are a component of immune modulation in red blood cell transfusion.

Marion Klea Pinheiro1,2,3,4, Marie Tamagne1,2,3,4, Rahma Elayeb1,2,3,4, Muriel Andrieu5, France Pirenne1,2,3,4, Benoît Vingert1,2,3,4.   

Abstract

Patients may display alloimmunization following transfusion. Microparticles (MPs) released into the blood are present in transfusion products. We show that MPs can modulate the immune system, CD4+ T-cell, and humoral responses, through their concentration, cellular origin and phenotype, and should therefore be considered to reduce the immune impact of transfusion.
© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Alloimmunization; Blood extracellular vesicles; CD4+ T-cell response

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Year:  2020        PMID： 32379351     DOI： 10.1002/eji.201948481

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  3 in total

Review 1.  Blood Cell-Derived Microvesicles in Hematological Diseases and beyond.

Authors:  Hara T Georgatzakou; Sotirios P Fortis; Effie G Papageorgiou; Marianna H Antonelou; Anastasios G Kriebardis
Journal:  Biomolecules       Date:  2022-06-08

2.  Autologous blood extracellular vesicles and specific CD4+ T-cell co-activation.

Authors:  Déborah Neyrinck-Leglantier; Marie Tamagne; Sasha L'honoré; Léonie Cagnet; Sadaf Pakdaman; Alexandre Marchand; France Pirenne; BenoÎt Vingert
Journal:  Front Immunol       Date:  2022-09-12       Impact factor: 8.786

3.  Is fresh, leucodepleted, whole blood transfusion superior to blood component transfusion in pediatric patients undergoing spinal deformity surgeries? A prospective, randomized study analyzing postoperative serological parameters and clinical recovery.

Authors:  P Keerthi Vasan; S Rajasekaran; Vibhu Krishnan Viswanathan; Ajoy Prasad Shetty; Rishi Mugesh Kanna
Journal:  Eur Spine J       Date:  2021-03-16       Impact factor: 3.134
  3 in total

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