| Literature DB >> 32378648 |
Ziyi Li1, Xiaojie Wang1, Donglin Cao2, Ruilin Sun3, Cheng Li4, Guowei Li1,5.
Abstract
The outbreak of SARS-CoV-2 rapidly spread across China and worldwide. Remdesivir had been proposed as a promising option for treating coronavirus disease 2019 (COVID-19). We provided a rapid review to critically assess the potential anti-coronavirus effect of remdesivir on COVID-19 and other coronaviruses based on the most up-to-date evidence. Even though remdesivir was proposed as a promising option for treating COVID-19 based on laboratory experiments and reports from compassionate use, its safety and effect in humans requires high-quality evidence from well-designed and adequately-powered clinical trials for further clarification.Entities:
Keywords: COVID-19; SARS-CoV-2; effect; remdesivir; safety
Year: 2020 PMID: 32378648 DOI: 10.5582/ddt.2020.01015
Source DB: PubMed Journal: Drug Discov Ther ISSN: 1881-7831