Literature DB >> 32374749

Strand breaks and chemical modification of intracellular DNA induced by cold atmospheric pressure plasma irradiation.

Hirofumi Kurita1, Natsuki Haruta1, Yoshito Uchihashi1, Takahito Seto1, Kazunori Takashima1.   

Abstract

DNA damage in the A549 human lung cancer cell line treated with cold plasma irradiation was investigated. We confirmed that cold atmospheric plasma generated reactive oxygen and nitrogen species (RONS) in a liquid, and the intracellular RONS level was increased in plasma-irradiated cells. However, a notable decrease in cell viability was not observed 24 hours after plasma irradiation. Because RONS induce oxidative damage in cells, strand breaks and chemical modification of DNA in the cancer cells were investigated. We found that 8-oxoguanine (8-oxoG) formation as well as DNA strand breaks, which have been thoroughly investigated, were induced by plasma irradiation. In addition, up-regulation of 8-oxoG repair enzyme was observed after plasma irradiation.

Entities:  

Year:  2020        PMID： 32374749     DOI： 10.1371/journal.pone.0232724

Source DB:  PubMed          Journal:  PLoS One        ISSN： 1932-6203            Impact factor:   3.240


  11 in total

1.  Noninvasive Physical Plasma as Innovative and Tissue-Preserving Therapy for Women Positive for Cervical Intraepithelial Neoplasia.

Authors:  Julia Marzi; Matthias B Stope; Melanie Henes; André Koch; Thomas Wenzel; Myriam Holl; Shannon L Layland; Felix Neis; Hans Bösmüller; Felix Ruoff; Markus Templin; Bernhard Krämer; Annette Staebler; Jakob Barz; Daniel A Carvajal Berrio; Markus Enderle; Peter M Loskill; Sara Y Brucker; Katja Schenke-Layland; Martin Weiss
Journal:  Cancers (Basel)       Date:  2022-04-12       Impact factor: 6.575

2.  Cell Type-Specific Anti-Adhesion Properties of Peritoneal Cell Treatment with Plasma-Activated Media (PAM).

Authors:  Myriam Holl; Marie-Lena Rasch; Lucas Becker; Anna-Lena Keller; Laura Schultze-Rhonhof; Felix Ruoff; Markus Templin; Silke Keller; Felix Neis; Franziska Keßler; Jürgen Andress; Cornelia Bachmann; Bernhard Krämer; Katja Schenke-Layland; Sara Y Brucker; Julia Marzi; Martin Weiss
Journal:  Biomedicines       Date:  2022-04-18

3.  Cold Atmospheric Plasma-Activated Media Improve Paclitaxel Efficacy on Breast Cancer Cells in a Combined Treatment Model.

Authors:  Cosmin-Teodor Mihai; Ilarion Mihaila; Maria Antoanela Pasare; Robert Mihai Pintilie; Mitica Ciorpac; Ionut Topala
Journal:  Curr Issues Mol Biol       Date:  2022-04-30       Impact factor: 2.976

Review 4.  Therapeutic Effects of Cold Atmospheric Plasma on Solid Tumor.

Authors:  Tianhao Min; Xin Xie; Kaijie Ren; Tuanhe Sun; Haonan Wang; Chengxue Dang; Hao Zhang
Journal:  Front Med (Lausanne)       Date:  2022-05-13

5.  Intracellular detection of singlet oxygen using fluorescent nanosensors.

Authors:  Peuli Nath; Sameer Sayel Hamadna; Leshern Karamchand; John Foster; Raoul Kopelman; Jacques G Amar; Aniruddha Ray
Journal:  Analyst       Date:  2021-06-14       Impact factor: 5.227

6.  Genome-Wide Comparison of the Target Genes of the Reactive Oxygen Species and Non-Reactive Oxygen Species Constituents of Cold Atmospheric Plasma in Cancer Cells.

Authors:  Hwee Won Ji; Heejoo Kim; Hyeon Woo Kim; Sung Hwan Yun; Jae Eun Park; Eun Ha Choi; Sun Jung Kim
Journal:  Cancers (Basel)       Date:  2020-09-16       Impact factor: 6.639

Review 7.  Effect of Cold Atmospheric Plasma on Epigenetic Changes, DNA Damage, and Possibilities for Its Use in Synergistic Cancer Therapy.

Authors:  Dušan Braný; Dana Dvorská; Ján Strnádel; Tatiana Matáková; Erika Halašová; Henrieta Škovierová
Journal:  Int J Mol Sci       Date:  2021-11-12       Impact factor: 5.923

8.  Patient-Derived Human Basal and Cutaneous Squamous Cell Carcinoma Tissues Display Apoptosis and Immunomodulation following Gas Plasma Exposure with a Certified Argon Jet.

Authors:  Fariba Saadati; Juliane Moritz; Julia Berner; Eric Freund; Lea Miebach; Iris Helfrich; Ingo Stoffels; Steffen Emmert; Sander Bekeschus
Journal:  Int J Mol Sci       Date:  2021-10-23       Impact factor: 5.923

Review 9.  Cold Atmospheric Plasma Targeting Hematological Malignancies: Potentials and Problems of Clinical Translation.

Authors:  Sebastiano Gangemi; Claudia Petrarca; Alessandro Tonacci; Mario Di Gioacchino; Caterina Musolino; Alessandro Allegra
Journal:  Antioxidants (Basel)       Date:  2022-08-17

Review 10.  Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology.

Authors:  Pavol Zubor; Yun Wang; Alena Liskova; Marek Samec; Lenka Koklesova; Zuzana Dankova; Anne Dørum; Karol Kajo; Dana Dvorska; Vincent Lucansky; Bibiana Malicherova; Ivana Kasubova; Jan Bujnak; Milos Mlyncek; Carlos Alberto Dussan; Peter Kubatka; Dietrich Büsselberg; Olga Golubnitschaja
Journal:  Int J Mol Sci       Date:  2020-10-27       Impact factor: 5.923
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