Literature DB >> 32372321

Nipple-sparing mastectomy for breast cancer close to the nipple: a single institution's 11-year experience.

Sunhyun Kim1, Seokwon Lee2, Youngtae Bae1, Seungju Lee3.   

Abstract

BACKGROUND: This study aimed to analyze our 11-year experience using NSM with immediate breast reconstruction in breast cancer.
METHODS: Between January 2007 and December 2015, 251 NSMs were performed on 251 women with breast cancer for therapeutic purpose at Pusan National University Hospital.
RESULTS: The clinical and pathologic mean tumor size was 3.1 cm. Based on preoperative imaging, mean distance between tumor and nipple was 2.5 cm. Among 251 tumors, 119 cases (47.4%) and 69 cases (27.5%) with a distances ≤ 2 cm and ≤ 1 cm, respectively, were detected. There were 11 patients (4.4%) with locoregional recurrences during the mean follow-up period of 68.0 months. Of these 11 cases, one (0.4%) had local recurrence in the retained NAC, and the others had recurrence in the chest wall or skin.
CONCLUSION: Unless clinical and histological evidence of nipple involvement, NSM can be an oncologically safe surgical option for breast cancer, even if the tumor is located close to the nipple.

Entities:  

Keywords:  Nipple-sparing mastectomy; Oncologic safety; Tumor size; Tumor-to-nipple distance

Year:  2020        PMID: 32372321     DOI: 10.1007/s12282-020-01104-0

Source DB:  PubMed          Journal:  Breast Cancer        ISSN: 1340-6868            Impact factor:   4.239


  2 in total

Review 1.  Clinical outcomes of patients after nipple-sparing mastectomy and reconstruction based on the expander/implant technique.

Authors:  Uhi Toh; Miki Takenaka; Nobutaka Iwakuma; Yoshito Akagi
Journal:  Surg Today       Date:  2020-11-13       Impact factor: 2.549

2.  Oncological safety of immediate breast reconstruction with skin- or nipple-sparing mastectomy: the value of tumor-to-dermis distance measured by preoperative ultrasonography.

Authors:  Takaaki Fujii; Yuko Nakazawa; Misato Ogino; Sayaka Obayashi; Reina Yajima; Chikako Honda; Hideharu Nakamura; Takaya Makiguchi; Ken Shirabe
Journal:  World J Surg Oncol       Date:  2021-03-12       Impact factor: 2.754

  2 in total

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