| Literature DB >> 32371008 |
Emily Cheng1, Neeha Gambhirrao2, Rohani Patel3, Aufia Zhowandai4, Jan Rychtář5, Dewey Taylor6.
Abstract
Poliomyelitis is a worldwide disease that has nearly been eradicated thanks to the Global Polio Eradication Initiative. Nevertheless, the disease is currently still endemic in three countries. In this paper, we incorporate the vaccination in a two age-class model of polio dynamics. Our main objective is to see whether mandatory vaccination policy is needed or if polio could be almost eradicated by a voluntary vaccination. We perform game theoretical analysis and compare the herd immunity vaccination levels with the Nash equilibrium vaccination levels. We show that the gap between two vaccination levels is too large. We conclude that the mandatory vaccination policy is therefore needed to achieve a complete eradication.Entities:
Keywords: Age-structured model; Game theory; Nash equilibrium; Polio; Vaccination
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Year: 2020 PMID: 32371008 DOI: 10.1016/j.jtbi.2020.110298
Source DB: PubMed Journal: J Theor Biol ISSN: 0022-5193 Impact factor: 2.691