Literature DB >> 32368518

Improving sputum collection processes to increase tuberculosis case finding among HIV-positive persons in Botswana.

U Mathebula1, C Emerson2, T Agizew1, S Pals2, R Boyd1,3, A Mathoma1, J Basotli1, G Rankgoane-Pono4, C Serumola1, A Date2, A F Auld2, A Finlay1,3.   

Abstract

SETTING: Twenty-two human immunodeficiency virus (HIV) clinics in Botswana.
OBJECTIVE: To compare sputum collection rates, sputum quality and volume, and tuberculosis (TB) diagnosis rates before and after field efforts to improve sputum collection among individuals newly diagnosed with HIV with TB symptoms.
DESIGN: Newly diagnosed individuals living with HIV attending 22 HIV clinics in Botswana were screened for TB from August 2012 to March 2014. Starting in May 2013, a field intervention composed of the introduction of a tracking log for presumed TB patients, and patient instructions and sputum induction to improve sputum collection rates was implemented.
RESULTS: Prior to the intervention, sputum collection rates were 44.1% (384/870). Subsequently, sputum collection increased to 58.3% (579/993) (P < 0.001). Sputum quality and volume also improved. Although rates of TB diagnosis increased from 9.7% (84/870) to 12.5% (120/993), this difference was not significant (P = 0.143).
CONCLUSION: Sputum collection rates among presumptive TB cases, as well as sputum quality and volume improved after implementation of the field intervention. To improve sputum collection rates, efforts at the program level should be ongoing.
© 2020 The Union.

Entities:  

Keywords:  Botswana; Xpert; healthcare worker; people living with HIV; tuberculosis

Year:  2020        PMID: 32368518      PMCID: PMC7181360          DOI: 10.5588/pha.19.0051

Source DB:  PubMed          Journal:  Public Health Action        ISSN: 2220-8372


  21 in total

1.  Better patient instruction for sputum sampling can improve microscopic tuberculosis diagnosis.

Authors:  B Alisjahbana; R van Crevel; H Danusantoso; T Gartinah; E S Soemantri; R H H Nelwan; J W M van der Meer
Journal:  Int J Tuberc Lung Dis       Date:  2005-07       Impact factor: 2.373

Review 2.  HIV infection-related tuberculosis: clinical manifestations and treatment.

Authors:  Timothy R Sterling; Paul A Pham; Richard E Chaisson
Journal:  Clin Infect Dis       Date:  2010-05-15       Impact factor: 9.079

3.  How well does the process of screening and diagnosis work for HIV-infected persons identified with presumptive tuberculosis who are attending HIV care and treatment clinics in Harare city, Zimbabwe?

Authors:  Kudakwashe C Takarinda; Regis Choto; Charles Sandy; Tsitsi Apollo; Clemence Duri; Freeman Dube; Amon Mpofu; Collins Timire; Owen Mugurungi; Victor Makaza; Roy Tapera; Anthony D Harries
Journal:  Trans R Soc Trop Med Hyg       Date:  2018-10-01       Impact factor: 2.184

4.  Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study.

Authors:  Catharina C Boehme; Mark P Nicol; Pamela Nabeta; Joy S Michael; Eduardo Gotuzzo; Rasim Tahirli; Ma Tarcela Gler; Robert Blakemore; William Worodria; Christen Gray; Laurence Huang; Tatiana Caceres; Rafail Mehdiyev; Lawrence Raymond; Andrew Whitelaw; Kalaiselvan Sagadevan; Heather Alexander; Heidi Albert; Frank Cobelens; Helen Cox; David Alland; Mark D Perkins
Journal:  Lancet       Date:  2011-04-18       Impact factor: 79.321

5.  Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings: individual participant data meta-analysis of observational studies.

Authors:  Haileyesus Getahun; Wanitchaya Kittikraisak; Charles M Heilig; Elizabeth L Corbett; Helen Ayles; Kevin P Cain; Alison D Grant; Gavin J Churchyard; Michael Kimerling; Sarita Shah; Stephen D Lawn; Robin Wood; Gary Maartens; Reuben Granich; Anand A Date; Jay K Varma
Journal:  PLoS Med       Date:  2011-01-18       Impact factor: 11.069

6.  Time to first consultation, diagnosis and treatment of TB among patients attending a referral hospital in Northwest, Ethiopia.

Authors:  Solomon A Yimer; Gunnar A Bjune; Carol Holm-Hansen
Journal:  BMC Infect Dis       Date:  2014-01-10       Impact factor: 3.090

7.  Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda.

Authors:  Amanda J Meyer; Collins Atuheire; William Worodria; Samuel Kizito; Achilles Katamba; Ingvar Sanyu; Alfred Andama; Irene Ayakaka; Adithya Cattamanchi; Freddie Bwanga; Laurence Huang; J Lucian Davis
Journal:  PLoS One       Date:  2017-07-07       Impact factor: 3.240

8.  The effect of sputum quality and volume on the yield of bacteriologically-confirmed TB by Xpert MTB/RIF and smear.

Authors:  Onani Zimba; Tsaone Tamuhla; Joyce Basotli; Gaoraelwe Letsibogo; Sherri Pals; Unami Mathebula; Anikie Mathoma; Christopher Serumola; Kitso Ramogale; Rosanna Boyd; Tiffany Tran; Alyssa Finlay; Andrew Auld; Anand Date; Heather Alexander; Violet Chihota; Tefera Agizew
Journal:  Pan Afr Med J       Date:  2019-06-13

9.  Incidence and determinants of tuberculosis among adults initiating antiretroviral therapy--Mozambique, 2004-2008.

Authors:  Andrew F Auld; Francisco Mbofana; Ray W Shiraishi; Charity Alfredo; Mauro Sanchez; Tedd V Ellerbrock; Lisa J Nelson
Journal:  PLoS One       Date:  2013-01-22       Impact factor: 3.240

Review 10.  Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings: a systematic review and meta-analysis.

Authors:  Rishi K Gupta; Sebastian B Lucas; Katherine L Fielding; Stephen D Lawn
Journal:  AIDS       Date:  2015-09-24       Impact factor: 4.177

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  2 in total

1.  The absence of evidence of cure is not a risk for recurrent TB among patients treated for TB.

Authors:  L Mantshonyane; B Kgwaadira; R Gross
Journal:  Int J Tuberc Lung Dis       Date:  2021-06-01       Impact factor: 3.427

2.  Interventions to improve linkage along the HIV-tuberculosis care cascades in low- and middle-income countries: A systematic review and meta-analysis.

Authors:  Angela Salomon; Stephanie Law; Cheryl Johnson; Annabel Baddeley; Ajay Rangaraj; Satvinder Singh; Amrita Daftary
Journal:  PLoS One       Date:  2022-05-12       Impact factor: 3.752

  2 in total

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