Sitara H Hirji1, Jeffrey M Liebmann1, Donald C Hood2, George A Cioffi1, Dana M Blumberg3. 1. Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA. 2. Departments of Psychology and Ophthalmology, Columbia University, New York, New York, USA. 3. Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: dmb2196@cumc.columbia.edu.
Abstract
PURPOSE: This report examines the relationship between glaucomatous macular damage and facial recognition. Additionally, it assesses the role of contrast sensitivity (CS) as an intermediary step in the causal pathway between macular damage and impairment of facial recognition. DESIGN: Prospective cross-sectional study METHODS: . SETTING: Tertiary care center STUDY POPULATION: 144 eyes of 72 participants with a diagnosis of open angle glaucoma in one or both eyes and a visual acuity of 20/40 or better in each eye. The presence or absence of macular damage was determined by comparing corresponding regions of the retinal nerve fiber layer and the retinal ganglion cell layer spectral domain optical coherence tomography (SD-OCT) with the 10-2 visual field (VF). Better and worse eye was determined by 10-2 VF mean deviations (MD). INTERVENTION: (1) Macular function as measured by 10-2 VF. (2) CS as measured by the Freiburg Visual Acuity and Contrast Test (FrACT). MAIN OUTCOME MEASURE: Cambridge Face Memory Test scores (CFMT) RESULTS: Regardless of eye, there was a significant correlation between facial recogntion and 10-2 VF MD (p<0.0001 better, worse eye). The 10-2 VF MD remained a significant predictor of facial recogntion after adjusting for potential confounders including glaucoma severity, CS, age and visual acuity (p=0.004 better eye, p=0.019 worse eye). CONCLUSIONS: Even with good central visual acuity, patients with glaucomatous macular damage exhibit diminished facial recognition, which is partly mediated through diminished CS.
PURPOSE: This report examines the relationship between glaucomatous macular damage and facial recognition. Additionally, it assesses the role of contrast sensitivity (CS) as an intermediary step in the causal pathway between macular damage and impairment of facial recognition. DESIGN: Prospective cross-sectional study METHODS: . SETTING: Tertiary care center STUDY POPULATION: 144 eyes of 72 participants with a diagnosis of open angle glaucoma in one or both eyes and a visual acuity of 20/40 or better in each eye. The presence or absence of macular damage was determined by comparing corresponding regions of the retinal nerve fiber layer and the retinal ganglion cell layer spectral domain optical coherence tomography (SD-OCT) with the 10-2 visual field (VF). Better and worse eye was determined by 10-2 VF mean deviations (MD). INTERVENTION: (1) Macular function as measured by 10-2 VF. (2) CS as measured by the Freiburg Visual Acuity and Contrast Test (FrACT). MAIN OUTCOME MEASURE: Cambridge Face Memory Test scores (CFMT) RESULTS: Regardless of eye, there was a significant correlation between facial recogntion and 10-2 VF MD (p<0.0001 better, worse eye). The 10-2 VF MD remained a significant predictor of facial recogntion after adjusting for potential confounders including glaucoma severity, CS, age and visual acuity (p=0.004 better eye, p=0.019 worse eye). CONCLUSIONS: Even with good central visual acuity, patients with glaucomatous macular damage exhibit diminished facial recognition, which is partly mediated through diminished CS.
Authors: Angela Y Chang; Emmanouil Tsamis; Dana M Blumberg; Lama A Al-Aswad; George A Cioffi; Donald C Hood; Jeffrey M Liebmann; C G De Moraes Journal: J Glaucoma Date: 2022-03-23 Impact factor: 2.290
Authors: Sharon A Bentley; Alex A Black; Gregory P Hindmarsh; Cynthia Owsley; Joanne M Wood Journal: Transl Vis Sci Technol Date: 2022-09-01 Impact factor: 3.048