Tung-Mei Kuang1, Sudha Xirasagar2, Yi-Wei Kao3, Ben-Chang Shia4, Herng-Ching Lin5. 1. Department of Ophthalmology, Taipei Veterans General Hospital; School of Medicine, National Yang-Ming University; Research Center of Sleep Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. 2. Department of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, USA. 3. Big Data Research Center, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Business Administration, College of Management, Fu Jen Catholic University, New Taipei City, Taiwan. 4. College of Management, Taipei Medical University, Taipei, Taiwan; Executive Master Program of Business Administration in Biotechnology, College of management, Taipei Medical University, Taipei, Taiwan. 5. Sleep Research Center, Taipei Medical University Hospital, Taipei, Taiwan; School of Health Care Administration, College of Management, Taipei Medical University, Taipei, Taiwan. Electronic address: henry11111@tmu.edu.tw.
Abstract
PURPOSE: To examine the association between systemic hypertension (HTN) and primary open angle glaucoma (POAG) using Taiwan's nationwide health insurance claims data. DESIGN: A case-control study METHODS: Data for this case-control study were retrieved from the Taiwan National Health Insurance. Research Database All 112,929 newly diagnosed patients with POAG from January 2010 through December 2015 (cases) and 449,840 propensity score-matched controls from Taiwan's National Health Insurance system. We performed multiple logistic regression analysis were to estimate the odds (ORs) of prior HTN among cases vs. controls. RESULTS: Of total 562,300 study patients, 296,975 (52.81%) had HTN prior to the index date, 63,528 (56.49%) among cases and 233,447 (51.90%) among controls (p<0.001). POAG was significantly associated with prior HTN (OR=1.31, 95% CI=1.29∼1.33) after adjusting for age, sex, monthly income, geographic location and residential urbanization level, hyperlipidemia, diabetes, coronary heart disease, migraine, hypotension and obstructive sleep apnea syndrome. CONCLUSIONS: POAG is associated with pre-existing HTN suggesting that internal medicine/family medicine physicians should refer patients with hypertension periodically for regular ophthalmological examinations and ophthalmologists should alert patients with glaucoma to have their blood pressure regularly monitored.
PURPOSE: To examine the association between systemic hypertension (HTN) and primary open angle glaucoma (POAG) using Taiwan's nationwide health insurance claims data. DESIGN: A case-control study METHODS: Data for this case-control study were retrieved from the Taiwan National Health Insurance. Research Database All 112,929 newly diagnosed patients with POAG from January 2010 through December 2015 (cases) and 449,840 propensity score-matched controls from Taiwan's National Health Insurance system. We performed multiple logistic regression analysis were to estimate the odds (ORs) of prior HTN among cases vs. controls. RESULTS: Of total 562,300 study patients, 296,975 (52.81%) had HTN prior to the index date, 63,528 (56.49%) among cases and 233,447 (51.90%) among controls (p<0.001). POAG was significantly associated with prior HTN (OR=1.31, 95% CI=1.29∼1.33) after adjusting for age, sex, monthly income, geographic location and residential urbanization level, hyperlipidemia, diabetes, coronary heart disease, migraine, hypotension and obstructive sleep apnea syndrome. CONCLUSIONS: POAG is associated with pre-existing HTN suggesting that internal medicine/family medicine physicians should refer patients with hypertension periodically for regular ophthalmological examinations and ophthalmologists should alert patients with glaucoma to have their blood pressure regularly monitored.
Authors: Jesus D Melgarejo; Jan V Eijgen; Gladys E Maestre; Lama A Al-Aswad; Lutgarde Thijs; Luis J Mena; Joseph H Lee; Joseph D Terwilliger; Michele Petitto; Carlos A Chávez; Miguel Brito; Gustavo Calmon; Egle Silva; Dong-Mei Wei; Ella Cutsforth; Karel V Keer; C Gustavo De Moraes; Thomas Vanassche; Stefan Janssens; Ingeborg Stalmans; Peter Verhamme; Jan A Staessen; Zhen-Yu Zhang Journal: Am J Hypertens Date: 2022-08-01 Impact factor: 3.080
Authors: Yung-En Tsai; Yi-Hao Chen; Chien-An Sun; Chi-Hsiang Chung; Wu-Chien Chien; Ke-Hung Chien Journal: Int J Environ Res Public Health Date: 2022-02-19 Impact factor: 3.390