M J Maiden1,2,3, M E Finnis2,3,4, G J Duke5,6, Eys Huning7, Tme Crozier5,6,8,9, N Nguyen10, V Biradar3,11, C McArthur4,12, D Pilcher4,13,14. 1. Intensive Care Unit, Barwon Health, Geelong, Vic., Australia. 2. Intensive Care Unit, Royal Adelaide Hospital, Adelaide, SA, Australia. 3. Discipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia. 4. Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Clayton, Vic., Australia. 5. Intensive Care Service, Eastern Health, Box Hill Hospital, Box Hill, Vic., Australia. 6. Eastern Health Clinical School, Monash University, Clayton, Vic., Australia. 7. Department of Obstetrics & Gynaecology, Barwon Health, Geelong, Vic., Australia. 8. Intensive Care Unit, Monash Medical Centre, Monash Health, Clayton, Vic., Australia. 9. Department of Obstetrics & Gynaecology, Monash University, Monash Medical Centre, Clayton, Vic., Australia. 10. Intensive Care Unit, Nepean Hospital, Penrith, NSW, Australia. 11. Intensive Care Unit, The Lyell McEwin Hospital, Elizabeth Vale, SA, Australia. 12. Department of Critical Care Medicine, Auckland City Hospital, Auckland, New Zealand. 13. Department of Intensive Care, Alfred Health, Prahran, Vic., Australia. 14. Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcome and Resource Evaluation (CORE), Camberwell, Vic., Australia.
Abstract
OBJECTIVE: Describe the epidemiology of obstetric patients admitted to an Intensive Care Unit (ICU). DESIGN: Registry-based cohort study. SETTING: One hundred and eighty-three ICUs in Australia and New Zealand. POPULATION: Women aged 15-49 years, admitted to ICU between 2008 and 2017, classified as pregnant, postpartum or with an obstetric-related diagnosis. METHODS: Data were extracted from the Australia and New Zealand Intensive Care Society (ANZICS) Adult Patient Database and national agencies. MAIN OUTCOME MEASURES: Incidence of ICU admission, cohort characteristics, maternal outcomes and changes over time. RESULTS: The cohort comprised 16 063 patients. The annual number of obstetric ICU admissions increased, whereas their proportion of total ICU admissions (1.3%) did not change (odds ratio 1.02, 95% CI 0.99-1.04, P = 0.14). There were 10 518 (65%) with an obstetric-related ICU diagnosis, and 5545 (35%) with a non-obstetric ICU diagnosis. Mean (SD) age was 31 (6.4) years, 1463 (9.1%) were Indigenous, 2305 (14%) were transferred from another hospital, and 3008 (19%) received mechanical ventilation. Median [IQR] length of stay in hospital was 5.2 [3.1-7.9] days, which included 1.1 [0.7-1.8] days in ICU. There were 108 (0.7%) maternal deaths, most (n = 97, 90%) having a non-obstetric diagnosis. There was no change in risk-adjusted length of stay or mortality over time. CONCLUSIONS: Obstetric patients account for a stable proportion of ICU admissions in Australia and New Zealand. These patients typically have a short length of ICU stay and low hospital mortality. TWEETABLE ABSTRACT: Obstetric patients in Australia/New Zealand ICUs have a short length of ICU stay and low mortality.
OBJECTIVE: Describe the epidemiology of obstetric patients admitted to an Intensive Care Unit (ICU). DESIGN: Registry-based cohort study. SETTING: One hundred and eighty-three ICUs in Australia and New Zealand. POPULATION: Women aged 15-49 years, admitted to ICU between 2008 and 2017, classified as pregnant, postpartum or with an obstetric-related diagnosis. METHODS: Data were extracted from the Australia and New Zealand Intensive Care Society (ANZICS) Adult Patient Database and national agencies. MAIN OUTCOME MEASURES: Incidence of ICU admission, cohort characteristics, maternal outcomes and changes over time. RESULTS: The cohort comprised 16 063 patients. The annual number of obstetric ICU admissions increased, whereas their proportion of total ICU admissions (1.3%) did not change (odds ratio 1.02, 95% CI 0.99-1.04, P = 0.14). There were 10 518 (65%) with an obstetric-related ICU diagnosis, and 5545 (35%) with a non-obstetric ICU diagnosis. Mean (SD) age was 31 (6.4) years, 1463 (9.1%) were Indigenous, 2305 (14%) were transferred from another hospital, and 3008 (19%) received mechanical ventilation. Median [IQR] length of stay in hospital was 5.2 [3.1-7.9] days, which included 1.1 [0.7-1.8] days in ICU. There were 108 (0.7%) maternal deaths, most (n = 97, 90%) having a non-obstetric diagnosis. There was no change in risk-adjusted length of stay or mortality over time. CONCLUSIONS: Obstetric patients account for a stable proportion of ICU admissions in Australia and New Zealand. These patients typically have a short length of ICU stay and low hospital mortality. TWEETABLE ABSTRACT: Obstetric patients in Australia/New Zealand ICUs have a short length of ICU stay and low mortality.
Authors: Betty Anane-Fenin; Evans Kofi Agbeno; Joseph Osarfo; Douglas Aninng Opoku Anning; Abigail Serwaa Boateng; Sebastian Ken-Amoah; Anthony Ofori Amanfo; Leonard Derkyi-Kwarteng; Mohammed Mouhajer; Sarah Ama Amoo; Joycelyn Ashong; Ernestina Jeffery Journal: PLoS One Date: 2021-12-31 Impact factor: 3.240
Authors: Karishma P Ramlakhan; Diederik Gommers; Carmen E R M Jacobs; Khaoula Makouri; Johannes J Duvekot; Irwin K M Reiss; Arie Franx; Jolien W Roos-Hesselink; Jérôme M J Cornette Journal: BMC Womens Health Date: 2021-06-19 Impact factor: 2.809