Literature DB >> 3235648

Working memory and secondary memory deficits in Alzheimer's disease.

J T Becker1.   

Abstract

The memory loss associated with Alzheimer's Disease (AD) may have multiple cognitive components. Working Memory appears to be impaired due to failures of a Central Executive System. Secondary Memory, on the other hand, is affected due to poor encoding or mediational processes. An analysis of the performance of 71 AD patients on tests related to these neuropsychological constructs revealed that they could indeed be dissociated. In fact, individual patients were identified with significantly different, and unique, patterns of impairment which were consistent with the two-component model. These data, therefore, lend preliminary support for the notion of multiple cognitive impairments being responsible for the memory loss in AD.

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Year:  1988        PMID: 3235648     DOI: 10.1080/01688638808402811

Source DB:  PubMed          Journal:  J Clin Exp Neuropsychol        ISSN: 1380-3395            Impact factor:   2.475


  13 in total

Review 1.  Changes in cognition.

Authors:  Marilyn S Albert
Journal:  Neurobiol Aging       Date:  2011-12       Impact factor: 4.673

2.  Heterogeneity in Alzheimer's disease: progression rate segregated by distinct neuropsychological and cerebral metabolic profiles.

Authors:  U M Mann; E Mohr; M Gearing; T N Chase
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-10       Impact factor: 10.154

3.  Hypothesis: microtubules, a key to Alzheimer disease.

Authors:  S S Matsuyama; L F Jarvik
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

4.  Ecological assessment of executive functions in mild cognitive impairment and mild Alzheimer's disease.

Authors:  Ana Espinosa; Montserrat Alegret; Mercè Boada; Georgina Vinyes; Sergi Valero; Pablo Martínez-Lage; Jordi Peña-Casanova; James T Becker; Barbara A Wilson; Lluís Tárraga
Journal:  J Int Neuropsychol Soc       Date:  2009-07-02       Impact factor: 2.892

5.  APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516.

Authors:  Zhen Liu; Xiangwei Dai; Wuhai Tao; Huilan Liu; He Li; Caishui Yang; Junying Zhang; Xin Li; Yaojing Chen; Chao Ma; Jing Pei; Haohao Mao; Kewei Chen; Zhanjun Zhang
Journal:  Hum Brain Mapp       Date:  2018-03-24       Impact factor: 5.038

6.  Changes in brain morphology in Alzheimer disease and normal aging: is Alzheimer disease an exaggerated aging process?

Authors:  T Ohnishi; H Matsuda; T Tabira; T Asada; M Uno
Journal:  AJNR Am J Neuroradiol       Date:  2001-10       Impact factor: 3.825

Review 7.  The apolipoprotein E gene, attention, and brain function.

Authors:  Raja Parasuraman; Pamela M Greenwood; Trey Sunderland
Journal:  Neuropsychology       Date:  2002-04       Impact factor: 3.295

8.  Material-specific memory loss in probable Alzheimer's disease.

Authors:  J T Becker; O L Lopez; J Wess
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-12       Impact factor: 10.154

9.  Neuropsychological performance in advanced age: influences of demographic factors and Apolipoprotein E: findings from the Cache County Memory Study.

Authors:  Katheen A Welsh-Bohmer; Truls Ostbye; Linda Sanders; Carl F Pieper; Kathleen M Hayden; JoAnn T Tschanz; Maria C Norton
Journal:  Clin Neuropsychol       Date:  2008-06-10       Impact factor: 3.535

10.  Dual-tasking and gait in people with mild cognitive impairment. The effect of working memory.

Authors:  Manuel Montero-Odasso; Howard Bergman; Natalie A Phillips; Chek H Wong; Nadia Sourial; Howard Chertkow
Journal:  BMC Geriatr       Date:  2009-09-01       Impact factor: 3.921

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