Yigang Pei1,2,3, Siming Xie1, Wenzheng Li1, Xianjing Peng1, Qin Qin4,5, Qian Ye1, Mengsi Li1, Jiaxi Hu1, Jiale Hou1, Guijing Li6, Shuo Hu7,8. 1. Department of Radiology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People's Republic of China. 2. Key Laboratory of Biological, Nanotechnology of National Health Commission, Changsha, 410008, Hunan, People's Republic of China. 3. Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People's Republic of China. 4. Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. 5. Kirby Center, Kennedy Krieger Institute, Baltimore, MD, 21205, USA. 6. Simens Healthcare Ltd, Guangzhou Branch, Guangzhou, 510620, People's Republic of China. 7. Key Laboratory of Biological, Nanotechnology of National Health Commission, Changsha, 410008, Hunan, People's Republic of China. hushuo2019@163.com. 8. PET-CT Center, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People's Republic of China. hushuo2019@163.com.
Abstract
PURPOSE: To obtain the optimal simultaneous-multislice (SMS)-accelerated diffusion-weighted imaging (DWI) of the liver at 3.0 T MRI by systematically estimating the repeatability of apparent diffusion coefficient (ADC), signal-to-noise ratio (SNR) and image quality of different breathing schemes in comparison to standard DWI (STD) and other SMS sequences. METHODS: In this institutional review board-approved prospective study, hepatic DWIs (b = 50, 300, 600 s/mm2) were performed in 23 volunteers on 3.0 T MRI using SMS and STD with breath-hold (BH-SMS, BH-STD), free-breathing (FB-SMS, FB-STD) and respiratory-triggered (RT-SMS, RT-STD). Reduction of scan time with SMS-acceleration was calculated. ADC and SNR were measured in nine anatomic locations and image quality was assessed on all SMS and STD sequences. An optimal SMS-DWI was decided by systematically comparing the ADC repeatability, SNR and image quality among above DWIs. RESULTS: SMS-DWI reduced scan time significantly by comparison with corresponding STD-DWI (27 vs. 42 s for BH, 54 vs. 78 s for FB and 42 vs. 97 s for RT). In all DWIs, BH-SMS had the greatest intraobserver agreement (intraclass correlation coefficient (ICC): 0.920-0.944) and good interobserver agreement (ICC: 0.831-0.886) for ADC measurements, and had the best ADC repeatability (mean ADC absolute differences: 0.046-0.058 × 10-3mm2/s, limits of agreement (LOA): 0.010-0.013 × 10-3mm2/s) in nine locations. BH-SMS had the highest SNR in three representative sections except for RT-STD. There were no significant differences in image quality between BH-SMS and other DWI sequences (median BH-SMS: 4.75, other DWI: 4.5-5.0; P > 0.0.5). CONCLUSION: BH-SMS provides considerable scan time reduction with good image quality, sufficient SNR and highest ADC repeatability on 3.0 T MRI, which is thus recommended as the optimal hepatic DWI sequence for those subjects with adequate breath-holding capability.
PURPOSE: To obtain the optimal simultaneous-multislice (SMS)-accelerated diffusion-weighted imaging (DWI) of the liver at 3.0 T MRI by systematically estimating the repeatability of apparent diffusion coefficient (ADC), signal-to-noise ratio (SNR) and image quality of different breathing schemes in comparison to standard DWI (STD) and other SMS sequences. METHODS: In this institutional review board-approved prospective study, hepatic DWIs (b = 50, 300, 600 s/mm2) were performed in 23 volunteers on 3.0 T MRI using SMS and STD with breath-hold (BH-SMS, BH-STD), free-breathing (FB-SMS, FB-STD) and respiratory-triggered (RT-SMS, RT-STD). Reduction of scan time with SMS-acceleration was calculated. ADC and SNR were measured in nine anatomic locations and image quality was assessed on all SMS and STD sequences. An optimal SMS-DWI was decided by systematically comparing the ADC repeatability, SNR and image quality among above DWIs. RESULTS:SMS-DWI reduced scan time significantly by comparison with corresponding STD-DWI (27 vs. 42 s for BH, 54 vs. 78 s for FB and 42 vs. 97 s for RT). In all DWIs, BH-SMS had the greatest intraobserver agreement (intraclass correlation coefficient (ICC): 0.920-0.944) and good interobserver agreement (ICC: 0.831-0.886) for ADC measurements, and had the best ADC repeatability (mean ADC absolute differences: 0.046-0.058 × 10-3mm2/s, limits of agreement (LOA): 0.010-0.013 × 10-3mm2/s) in nine locations. BH-SMS had the highest SNR in three representative sections except for RT-STD. There were no significant differences in image quality between BH-SMS and other DWI sequences (median BH-SMS: 4.75, other DWI: 4.5-5.0; P > 0.0.5). CONCLUSION: BH-SMS provides considerable scan time reduction with good image quality, sufficient SNR and highest ADC repeatability on 3.0 T MRI, which is thus recommended as the optimal hepatic DWI sequence for those subjects with adequate breath-holding capability.
Authors: Jakob Weiss; Petros Martirosian; Jana Taron; Ahmed E Othman; Thomas Kuestner; Michael Erb; Jens Bedke; Fabian Bamberg; Konstantin Nikolaou; Mike Notohamiprodjo Journal: J Magn Reson Imaging Date: 2017-02-15 Impact factor: 4.813
Authors: Jana Taron; Petros Martirosian; Michael Erb; Thomas Kuestner; Nina F Schwenzer; Holger Schmidt; Valerie S Honndorf; Jakob Weiβ; Mike Notohamiprodjo; Konstantin Nikolaou; Christina Schraml Journal: J Magn Reson Imaging Date: 2016-02-26 Impact factor: 4.813
Authors: Jana Taron; Christina Schraml; Christina Pfannenberg; Matthias Reimold; Nina Schwenzer; Konstantin Nikolaou; Petros Martirosian; Ferdinand Seith Journal: Eur Radiol Date: 2018-02-26 Impact factor: 5.315
Authors: Thomas De Perrot; Christine Sadjo Zoua; Carl G Glessgen; Diomidis Botsikas; Lena Berchtold; Rares Salomir; Sophie De Seigneux; Harriet C Thoeny; Jean-Paul Vallée Journal: J Clin Med Date: 2022-03-30 Impact factor: 4.241