Arthur Hoffman1, Raja Atreya2, Timo Rath2, Markus F Neurath2. 1. Department of Internal Medicine III, Clinic Aschaffenburg-Alzenau, Aschaffenburg, Germany. 2. First Department of Medicine, Friedrich Alexander University Erlangen-Nuernberg, Erlangen, Germany.
Abstract
BACKGROUND: The advancement of innovative endoscopic technology in terms of improving the visualization of the mucosa has been of significant benefit. SUMMARY: Advancements in image resolution, software processing, and optical filter technology have resulted in several techniques complemental to traditional white light endoscopy. These new techniques provide a real-time optical diagnosis as well as virtual histology of detected lesions. Optical molecular imaging permits a functional assessment within cells. KEY MESSAGE: Optical molecular imaging provides an understanding of cellular processes and permits validation of the specificity of fluorescent tracers and the possibility of quantifying the signal.
BACKGROUND: The advancement of innovative endoscopic technology in terms of improving the visualization of the mucosa has been of significant benefit. SUMMARY: Advancements in image resolution, software processing, and optical filter technology have resulted in several techniques complemental to traditional white light endoscopy. These new techniques provide a real-time optical diagnosis as well as virtual histology of detected lesions. Optical molecular imaging permits a functional assessment within cells. KEY MESSAGE: Optical molecular imaging provides an understanding of cellular processes and permits validation of the specificity of fluorescent tracers and the possibility of quantifying the signal.
Authors: Bishnu P Joshi; Xiyu Duan; Richard S Kwon; Cyrus Piraka; B Joseph Elmunzer; Shaoying Lu; Emily F Rabinsky; David G Beer; Henry D Appelman; Scott R Owens; Rork Kuick; Nobuyuki Doguchi; D Kim Turgeon; Thomas D Wang Journal: Endoscopy Date: 2015-10-01 Impact factor: 10.093
Authors: Silas J Leavesley; Mikayla Walters; Carmen Lopez; Thomas Baker; Peter F Favreau; Thomas C Rich; Paul F Rider; Carole W Boudreaux Journal: J Biomed Opt Date: 2016-10-01 Impact factor: 3.170
Authors: James D Smith; Jeannine A Ruby; Karyn A Goodman; Leonard B Saltz; José G Guillem; Martin R Weiser; Larissa K Temple; Garrett M Nash; Philip B Paty Journal: Ann Surg Date: 2012-12 Impact factor: 12.969