Eri Inoue1, Hiroshi Doi2, Hajime Monzen3, Mikoto Tamura3, Masahiro Inada2, Kazuki Ishikawa2, Kiyoshi Nakamatsu2, Yasumasa Nishimura2. 1. Department of Radiation Oncology, Kindai University Faculty of Medicine, Osaka, Japan 1876c1@med.kindai.ac.jp. 2. Department of Radiation Oncology, Kindai University Faculty of Medicine, Osaka, Japan. 3. Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osaka, Japan.
Abstract
BACKGROUND/AIM: We evaluated the dosimetric profiles of manually generated volumetric-modulated arc therapy (VMAT) plans and performance of a commercial knowledge-based planning system (KBP) in treating breast cancer. MATERIALS AND METHODS: We defined the manually generated VMAT plan as the manual plan (MP). Twenty MPs were generated for left-sided breast cancer patients who underwent breast-conserving surgery and used to develop a KBP training set. The other five patients were used for validation. The dosimetric parameters among MPs, tangential irradiation plans (TPs), and KBP-VMAT plans (KBP-Ps) were compared. RESULTS: D95 and homogeneity of the planning target volume (PTV) were significantly higher and greater in MPs and KBP-Ps than in TPs. Lung V20, V40 The Dmean for the left anterior descending artery was lower in MPs and KBP-Ps than in TPs. KBP could save time in generating VMAT plans. CONCLUSION: MPs and KBP-Ps could ensure higher dose uniformity of PTV than TPs. KBP could faster generate comparable MPs for breast cancer. Copyright
BACKGROUND/AIM: We evaluated the dosimetric profiles of manually generated volumetric-modulated arc therapy (VMAT) plans and performance of a commercial knowledge-based planning system (KBP) in treating breast cancer. MATERIALS AND METHODS: We defined the manually generated VMAT plan as the manual plan (MP). Twenty MPs were generated for left-sided breast cancerpatients who underwent breast-conserving surgery and used to develop a KBP training set. The other five patients were used for validation. The dosimetric parameters among MPs, tangential irradiation plans (TPs), and KBP-VMAT plans (KBP-Ps) were compared. RESULTS: D95 and homogeneity of the planning target volume (PTV) were significantly higher and greater in MPs and KBP-Ps than in TPs. Lung V20, V40 The Dmean for the left anterior descending artery was lower in MPs and KBP-Ps than in TPs. KBP could save time in generating VMAT plans. CONCLUSION:MPs and KBP-Ps could ensure higher dose uniformity of PTV than TPs. KBP could faster generate comparable MPs for breast cancer. Copyright
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