Literature DB >> 32349891

Chronic Obstructive Pulmonary Disease Is Associated With Higher Rates of Venous Thromboemboli Following Primary Total Knee Arthroplasty.

Rushabh M Vakharia1, Curtis T Adams2, Afshin A Anoushiravani2, Joseph O Ehiorobo3, Michael A Mont4, Martin W Roche1.   

Abstract

BACKGROUND: There is discordance in the literature regarding the presence of chronic obstructive pulmonary disease (COPD) and the development of venous thromboemboli (VTEs). Therefore, the purpose of this study is to determine whether COPD patients undergoing primary total knee arthroplasty (TKA) have higher rates of (1) in-hospital lengths of stay (LOS); (2) readmissions; (3) VTEs; and (4) costs of care.
METHODS: COPD patients undergoing primary TKA were identified and matched to controls in a 1:5 ratio by age, gender, and medical comorbidities. Patients with a history of VTEs or hypercoagulable states were excluded. The query yielded 211,378 patients in the study (n = 35,230) and control (n = 176,148) cohorts. Outcomes analyzed included in-hospital LOS, readmission rates, VTEs, and costs of care. A P-value less than .01 was considered statistically significant.
RESULTS: COPD patients were found to have significantly longer in-hospital LOS (4 vs 3 days, P < .0001). Study group patients were also found to have significantly higher incidence and odds ratio (OR) of readmission rates (20.9% vs 16.3%; OR 1.36, P < .0001) and VTEs (1.75 vs .93; OR 1.18, P < .0001). Additionally, the study demonstrated that COPD patients incurred higher 90-day episode-of-care costs ($15,626.85 vs $14,471.29, P < .0001).
CONCLUSION: After adjusting for confounding variables, our study found an association between COPD and higher rates of developing VTEs following primary TKA. The study can be used by orthopedic surgeons to adequately counsel and educate these patients of the potential complications which may arise following their TKA.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  chronic obstructive pulmonary disease; costs; medicare; readmissions; total knee arthroplasty; venous thromboemboli

Mesh:

Year:  2020        PMID: 32349891     DOI: 10.1016/j.arth.2020.03.053

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  2 in total

1.  A nationwide analysis on the effects of chronic obstructive pulmonary disease following primary total shoulder arthroplasty for glenohumeral osteoarthritis.

Authors:  Brandon Amirian; Kyrillos M Akhnoukh; Asad M Ashraf; Samuel J Swiggett; Francis E Rosato; Rushabh M Vakharia; Ramin Sadeghpour; Afshin E Razi
Journal:  Shoulder Elbow       Date:  2021-02-25

2.  Chronic obstructive pulmonary disease is an independent risk factor for postoperative complications following operative treatment of distal radius fracture.

Authors:  Theodore Quan; Frank R Chen; Melina Recarey; Abhay Mathur; Tom Pollard; Alex Gu; Chapman Wei; Peter Howard; Jonathan Pribaz
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-06-29
  2 in total

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