Noriyuki Ohkura1, Kazuo Kasahara2, Satoshi Watanabe2, Johsuke Hara2, Miki Abo2, Takashi Sone2, Hideharu Kimura2, Munehisa Takata3, Masaya Tamura3, Isao Matsumoto3, Yusuke Nakade4, Shigeru Sanada5, Rie Tanaka6. 1. Department of Respiratory Medicine, Kanazawa University Hospital, Kanazawa, Japan, n-ohkura@med.kanazawa-u.ac.jp. 2. Department of Respiratory Medicine, Kanazawa University Hospital, Kanazawa, Japan. 3. Department of Thoracic, Cardiovascular, and General Surgery, Kanazawa University Hospital, Kanazawa, Japan. 4. Clinical Laboratory, Kanazawa University Hospital, Kanazawa, Japan. 5. Faculty of Health Sciences, Komatsu University, Komatsu, Japan. 6. College of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan.
Abstract
OBJECTIVE: The aim of this study was to determine the utility of dynamic-ventilatory digital radiography (DR) for pulmonary function assessment in patients with airflow limitation. METHODS: One hundred and eighteen patients with airflow limitation (72 patients with lung cancer before surgery, 35 patients with chronic obstructive pulmonary disease [COPD], 6 patients with asthma, and 5 patients with asthma-COPD overlap syndrome) were assessed with dynamic-ventilatory DR. The patients were instructed to inhale and exhale slowly and maximally. Sequential chest X-ray images were captured in 15 frames per second using a dynamic flat-panel imaging system. The relationship between the lung area and the rate of change in the lung area due to respiratory motion with respect to pulmonary function was analyzed. RESULTS: The rate of change in the lung area from maximum inspiration to maximum expiration (Rs ratio) was associated with the RV/TLC ratio (r = 0.48, p < 0.01) and the percentage of the predicted FEV1 (r = -0.33, p < 0.01) in patients with airflow limitations. The Rs ratio also decreased in an FEV1-dependent manner. CONCLUSION: The rate of change in the lung area due to respiratory motion evaluated with dynamic DR reflects air trapping. Dynamic DR is a potential tool for the comprehensive assessment of pulmonary function in patients with COPD.
OBJECTIVE: The aim of this study was to determine the utility of dynamic-ventilatory digital radiography (DR) for pulmonary function assessment in patients with airflow limitation. METHODS: One hundred and eighteen patients with airflow limitation (72 patients with lung cancer before surgery, 35 patients with chronic obstructive pulmonary disease [COPD], 6 patients with asthma, and 5 patients with asthma-COPD overlap syndrome) were assessed with dynamic-ventilatory DR. The patients were instructed to inhale and exhale slowly and maximally. Sequential chest X-ray images were captured in 15 frames per second using a dynamic flat-panel imaging system. The relationship between the lung area and the rate of change in the lung area due to respiratory motion with respect to pulmonary function was analyzed. RESULTS: The rate of change in the lung area from maximum inspiration to maximum expiration (Rs ratio) was associated with the RV/TLC ratio (r = 0.48, p < 0.01) and the percentage of the predicted FEV1 (r = -0.33, p < 0.01) in patients with airflow limitations. The Rs ratio also decreased in an FEV1-dependent manner. CONCLUSION: The rate of change in the lung area due to respiratory motion evaluated with dynamic DR reflects air trapping. Dynamic DR is a potential tool for the comprehensive assessment of pulmonary function in patients with COPD.
Authors: M R Miller; J Hankinson; V Brusasco; F Burgos; R Casaburi; A Coates; R Crapo; P Enright; C P M van der Grinten; P Gustafsson; R Jensen; D C Johnson; N MacIntyre; R McKay; D Navajas; O F Pedersen; R Pellegrino; G Viegi; J Wanger Journal: Eur Respir J Date: 2005-08 Impact factor: 16.671
Authors: Amany F Elbehairy; Casey E Ciavaglia; Katherine A Webb; Jordan A Guenette; Dennis Jensen; Sahar M Mourad; J Alberto Neder; Denis E O'Donnell Journal: Am J Respir Crit Care Med Date: 2015-06-15 Impact factor: 21.405
Authors: Dave Singh; Alvar Agusti; Antonio Anzueto; Peter J Barnes; Jean Bourbeau; Bartolome R Celli; Gerard J Criner; Peter Frith; David M G Halpin; Meilan Han; M Victorina López Varela; Fernando Martinez; Maria Montes de Oca; Alberto Papi; Ian D Pavord; Nicolas Roche; Donald D Sin; Robert Stockley; Jørgen Vestbo; Jadwiga A Wedzicha; Claus Vogelmeier Journal: Eur Respir J Date: 2019-05-18 Impact factor: 16.671
Authors: A Sonia Buist; Mary Ann McBurnie; William M Vollmer; Suzanne Gillespie; Peter Burney; David M Mannino; Ana M B Menezes; Sean D Sullivan; Todd A Lee; Kevin B Weiss; Robert L Jensen; Guy B Marks; Amund Gulsvik; Ewa Nizankowska-Mogilnicka Journal: Lancet Date: 2007-09-01 Impact factor: 79.321
Authors: Bartolome R Celli; Claudia G Cote; Jose M Marin; Ciro Casanova; Maria Montes de Oca; Reina A Mendez; Victor Pinto Plata; Howard J Cabral Journal: N Engl J Med Date: 2004-03-04 Impact factor: 91.245
Authors: Paul Albert; Alvar Agusti; Lisa Edwards; Ruth Tal-Singer; Julie Yates; Per Bakke; Bartolome R Celli; Harvey O Coxson; Courtney Crim; David A Lomas; William Macnee; Bruce Miller; Stephen Rennard; Edwin K Silverman; Jørgen Vestbo; Emiel Wouters; Peter Calverley Journal: Thorax Date: 2012-06-13 Impact factor: 9.139
Authors: Lucas M A Goossens; Inge Leimer; Norbert Metzdorf; Karin Becker; Maureen P M H Rutten-van Mölken Journal: BMC Pulm Med Date: 2014-10-18 Impact factor: 3.317