| Literature DB >> 32348156 |
Eric A Nauman1,2,3, Thomas M Talavage1,4, Paul S Auerbach5.
Abstract
Subconcussive head injury represents a pathophysiology that spans the expertise of both clinical neurology and biomechanical engineering. From both viewpoints, the terms injury and damage, presented without qualifiers, are synonymously taken to mean a tissue alteration that may be recoverable. For clinicians, concussion is evolving from a purely clinical diagnosis to one that requires objective measurement, to be achieved by biomedical engineers. Subconcussive injury is defined as subclinical pathophysiology in which underlying cellular- or tissue-level damage (here, to the brain) is not severe enough to present readily observable symptoms. Our concern is not whether an individual has a (clinically diagnosed) concussion, but rather, how much accumulative damage an individual can tolerate before they will experience long-term deficit(s) in neurological health. This concern leads us to look for the history of damage-inducing events, while evaluating multiple approaches for avoiding injury through reduction or prevention of the associated mechanically induced damage.Entities:
Keywords: MRI; TBI; concussion; contact sports; subconcussive injury
Year: 2020 PMID: 32348156 DOI: 10.1146/annurev-bioeng-091219-053447
Source DB: PubMed Journal: Annu Rev Biomed Eng ISSN: 1523-9829 Impact factor: 9.590