Literature DB >> 32348156

Mitigating the Consequences of Subconcussive Head Injuries.

Eric A Nauman1,2,3, Thomas M Talavage1,4, Paul S Auerbach5.   

Abstract

Subconcussive head injury represents a pathophysiology that spans the expertise of both clinical neurology and biomechanical engineering. From both viewpoints, the terms injury and damage, presented without qualifiers, are synonymously taken to mean a tissue alteration that may be recoverable. For clinicians, concussion is evolving from a purely clinical diagnosis to one that requires objective measurement, to be achieved by biomedical engineers. Subconcussive injury is defined as subclinical pathophysiology in which underlying cellular- or tissue-level damage (here, to the brain) is not severe enough to present readily observable symptoms. Our concern is not whether an individual has a (clinically diagnosed) concussion, but rather, how much accumulative damage an individual can tolerate before they will experience long-term deficit(s) in neurological health. This concern leads us to look for the history of damage-inducing events, while evaluating multiple approaches for avoiding injury through reduction or prevention of the associated mechanically induced damage.

Entities:  

Keywords:  MRI; TBI; concussion; contact sports; subconcussive injury

Year:  2020        PMID: 32348156     DOI: 10.1146/annurev-bioeng-091219-053447

Source DB:  PubMed          Journal:  Annu Rev Biomed Eng        ISSN: 1523-9829            Impact factor:   9.590


  3 in total

1.  Development of brain atlases for early-to-middle adolescent collision-sport athletes.

Authors:  Yukai Zou; Wenbin Zhu; Ho-Ching Yang; Ikbeom Jang; Nicole L Vike; Diana O Svaldi; Trey E Shenk; Victoria N Poole; Evan L Breedlove; Gregory G Tamer; Larry J Leverenz; Ulrike Dydak; Eric A Nauman; Yunjie Tong; Thomas M Talavage; Joseph V Rispoli
Journal:  Sci Rep       Date:  2021-03-19       Impact factor: 4.379

2.  Interface astrogliosis in contact sport head impacts and military blast exposure.

Authors:  Katharine J Babcock; Bobak Abdolmohammadi; Patrick T Kiernan; Ian Mahar; Jonathan D Cherry; Victor E Alvarez; Lee E Goldstein; Thor D Stein; Ann C McKee; Bertrand R Huber
Journal:  Acta Neuropathol Commun       Date:  2022-04-13       Impact factor: 7.801

3.  A preliminary model of football-related neural stress that integrates metabolomics with transcriptomics and virtual reality.

Authors:  Nicole L Vike; Sumra Bari; Khrystyna Stetsiv; Alexa Walter; Sharlene Newman; Keisuke Kawata; Jeffrey J Bazarian; Zoran Martinovich; Eric A Nauman; Thomas M Talavage; Linda Papa; Semyon M Slobounov; Hans C Breiter
Journal:  iScience       Date:  2021-12-15
  3 in total

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