| Literature DB >> 32344506 |
Domenico Russo1, Rocco Tripepi2, Fabio Malberti3, Biagio Di Iorio4, Bernadette Scognamiglio1, Luca Di Lullo5, Immacolata Gaia Paduano1, Giovanni Luigi Tripepi2, Vincenzo Antonio Panuccio6.
Abstract
The authors wish to make the following corrections to the previous publication [...].Entities:
Year: 2020 PMID: 32344506 PMCID: PMC7230265 DOI: 10.3390/jcm9041224
Source DB: PubMed Journal: J Clin Med ISSN: 2077-0383 Impact factor: 4.241
Patients’ Characteristics.
| Total Group | Naïve Group | Switch Group | ||
|---|---|---|---|---|
| Age (years) | 61 ± 14 | 64 ± 14 | 59 ± 14 | 0.04 |
| Male (%) | 57 | 52 | 60 | 0.32 |
| Dialysis vintage (month) | 58 (IQR 32–102) | 35 (IQR 14–63) | 69 (IQR 48–120) | <0.001 |
| Diabetes (%) | 25 | 31 | 22 | 0.23 |
| Cardiovascular comorbidities (%) | 73 | 70 | 75 | 0.53 |
| iPTH (pg/mL) | 636 (IQR 493–916) | 602 (IQR 509–800) | 664 (IQR 495–947) | 0.67 |
| Serum Calcium (mEq/L) | 9.0 ± 1.0 | 9.1 ± 0.7 | 9.0 ± 1.1 | 0.60 |
| Serum Phosphate (mg/dL) | 5.6 ± 1.4 | 5.5 ± 1.4 | 5.6 ± 1.4 | 0.83 |
| Alkaline Phosphate (U.I./L) | 131 (IQR 83–201) | 111 (IQR 74–159) | 148 (IQR 88–221) | 0.02 |
| Hb (gr/dL) | 11.1 ± 1.4 | 11.0 ± 1.2 | 11.1 ± 1.4 | 0.58 |
| ESA treatment (%) | 87 | 88 | 87 | 0.97 |
| Phosphate binders therapy (%) | 96 | 93 | 97 | 0.17 |
| Calcium containing binders (%) | 18 | 25 | 14 | 0.09 |
| Vitamin D therapy (%) | 75 | 83 | 71 | 0.09 |
| Native Vitamin D therapy (%) | 5 | 4 | 6 | 0.59 |
| Previous cinacalcet treatment (%) | 67 | 0 | 100 | N/A |
IQR, interquartile range; iPTH, intact parathyroid hormone; Hb, hemoglobin; ESA, erythropoietin-stimulating agent.
Cases of hypocalcemia.
| Days after Parsabiv | <7.0 mEq/L | ≥7.0 or <7.5 mEq/L | ≥7.5 or <8.3 mEq/L |
|---|---|---|---|
| 30 | 3/168 (1.8%) | 0 | 25/168 (14.9%)) |
| 60 | 1/129 (0.8%) | 7/129 (5.4%) | 28/129 (21.7%) |
| 90 | 2/111 (1.8%) | 2/111 (1.8%) | 27/111 (24.3%) |
| 120 | 1/80 (1.3%) | 1/80 (1.3%) | 21/80 (26.2%) |
| 150 | 1/61 (1.6%) | 6/61 (9.8%) | 11/61 (18.0%) |
| 180 | 0 | 1/44 (2.3%) | 11/44 (25.0%) |
| 210 | 0 | 1/51 (2.0%) | 15/51 (29.4%) |
Figure 1P for the trend of intact parathyroid hormone (iPTH) (panel a), serum calcium (panel b), serum phosphate (panel c), alkaline phosphatase (panel d) over time was obtained using linear regression models weighted for patients’ identification (see methods for more details).
Patients’ Characteristics.
| Total Group | Naïve Group | Switch Group | ||
|---|---|---|---|---|
| Age (years) | 61 ± 14 | 64 ± 14 | 59 ± 14 | 0.04 |
| Male (%) | 57 | 52 | 60 | 0.32 |
| Dialysis vintage (month) | 58 (IQR 32–102) | 35 (IQR 14–63) | 69 (IQR 48–120) | <0.001 |
| Diabetes (%) | 25 | 31 | 22 | 0.23 |
| Cardiovascular comorbidities (%) | 73 | 70 | 75 | 0.53 |
| iPTH (pg/mL) | 636 (IQR 493–916) | 602 (IQR 509–800) | 664 (IQR 495–947) | 0.67 |
| Serum Calcium (mg/dL) | 9.0 ± 1.0 | 9.1 ± 0.7 | 9.0 ± 1.1 | 0.60 |
| Serum Phosphate (mg/dL) | 5.6 ± 1.4 | 5.5 ± 1.4 | 5.6 ± 1.4 | 0.83 |
| Alkaline Phosphate (U.I./L) | 131 (IQR 83–201) | 111 (IQR 74–159) | 148 (IQR 88–221) | 0.02 |
| Hb (gr/dL) | 11.1 ± 1.4 | 11.0 ± 1.2 | 11.1 ± 1.4 | 0.58 |
| ESA treatment (%) | 87 | 88 | 87 | 0.97 |
| Phosphate binders therapy (%) | 96 | 93 | 97 | 0.17 |
| Calcium containing binders (%) | 18 | 25 | 14 | 0.09 |
| Vitamin D therapy (%) | 75 | 83 | 71 | 0.09 |
| Native Vitamin D therapy (%) | 5 | 4 | 6 | 0.59 |
| Previous cinacalcet treatment (%) | 67 | 0 | 100 | N/A |
IQR, interquartile range; iPTH, intact parathyroid hormone; Hb, hemoglobin; ESA, erythropoietin-stimulating agent.
Cases of hypocalcemia.
| Days after Etelcalcetide | <7.0 mg/dL | ≥7.0 or ≤7.5 mg/dL | >7.5 or <8.3 mg/dL |
|---|---|---|---|
| 30 | 3/168 (1.8%) | 0 | 25/168 (14.9%)) |
| 60 | 1/129 (0.8%) | 7/129 (5.4%) | 28/129 (21.7%) |
| 90 | 2/111 (1.8%) | 2/111 (1.8%) | 27/111 (24.3%) |
| 120 | 1/80 (1.3%) | 1/80 (1.3%) | 21/80 (26.2%) |
| 150 | 1/61 (1.6%) | 6/61 (9.8%) | 11/61 (18.0%) |
| 180 | 0 | 1/44 (2.3%) | 11/44 (25.0%) |
| 210 | 0 | 1/51 (2.0%) | 15/51 (29.4%) |
Figure 1P for the trend of intact parathyroid hormone (iPTH) (panel a), serum calcium (panel b), serum phosphate (panel c), alkaline phosphatase (panel d) over time was obtained using linear regression models weighted for patients’ identification (see methods for more details).