Literature DB >> 32342305

Chemogenetic Activation of Glutamatergic Neurons in the Juvenile Rat Cortex Reduces Anxiety.

N N Dygalo1,2, D A Lanshakov3, N P Komysheva3, U S Drozd3,4, E V Shaburova3,4, E V Sukhareva3,4, G T Shishkina3.   

Abstract

Abstract-Chemogenetic activation of glutamatergic neurons of the prefrontal cortex reduces the manifestations of psychoemotional anxiety during the juvenile period of ontogenesis. This result is the first evidence of feasibility of targeted chemogenetic control of neuronal activity during the early stages of brain development.

Entities:  

Keywords:  anxiety; chemogenetics; glutamatergic neurons; juvenile period of ontogenesis; prefrontal cortex

Year:  2020        PMID： 32342305     DOI： 10.1134/S1607672920010056

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  10 in total

Review 1.  The adolescent brain and age-related behavioral manifestations.

Authors:  L P Spear
Journal:  Neurosci Biobehav Rev       Date:  2000-06       Impact factor: 8.989

2.  Optogenetic Stimulation Increases Level of Antiapoptotic Protein Bcl-xL in Neurons.

Authors:  D A Lanshakov; U S Drozd; N N Dygalo
Journal:  Biochemistry (Mosc)       Date:  2017-03       Impact factor: 2.487

Review 3.  A next step in adeno-associated virus-mediated gene therapy for neurological diseases: regulation and targeting.

Authors:  Abdelwahed Chtarto; Olivier Bockstael; Terence Tshibangu; Olivier Dewitte; Marc Levivier; Liliane Tenenbaum
Journal:  Br J Clin Pharmacol       Date:  2013-08       Impact factor: 4.335

Review 4.  Chemogenetic tools to interrogate brain functions.

Authors:  Scott M Sternson; Bryan L Roth
Journal:  Annu Rev Neurosci       Date:  2014-06-16       Impact factor: 12.449

5.  Dexamethasone-induced acute excitotoxic cell death in the developing brain.

Authors:  Dmitriy A Lanshakov; Ekaterina V Sukhareva; Tatjana S Kalinina; Nikolay N Dygalo
Journal:  Neurobiol Dis       Date:  2016-02-09       Impact factor: 5.996

Review 6.  The mouse light/dark box test.

Authors:  Michel Bourin; Martine Hascoët
Journal:  Eur J Pharmacol       Date:  2003-02-28       Impact factor: 4.432

7.  Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive.

Authors:  Sanghee Yun; Ryan P Reynolds; Iraklis Petrof; Alicia White; Phillip D Rivera; Amir Segev; Adam D Gibson; Maiko Suarez; Matthew J DeSalle; Naoki Ito; Shibani Mukherjee; Devon R Richardson; Catherine E Kang; Rebecca C Ahrens-Nicklas; Ivan Soler; Dane M Chetkovich; Saïd Kourrich; Douglas A Coulter; Amelia J Eisch
Journal:  Nat Med       Date:  2018-04-16       Impact factor: 53.440

8.  Limited prefrontal cortical regulation over the basolateral amygdala in adolescent rats.

Authors:  Ryan A Selleck; Wei Zhang; Hannah D Samberg; Mallika Padival; J Amiel Rosenkranz
Journal:  Sci Rep       Date:  2018-11-21       Impact factor: 4.379

Review 9.  Designer receptor technology for the treatment of epilepsy.

Authors:  Andreas Lieb; Mikail Weston; Dimitri M Kullmann
Journal:  EBioMedicine       Date:  2019-05-09       Impact factor: 8.143

Review 10.  Maturational Changes in Prefrontal and Amygdala Circuits in Adolescence: Implications for Understanding Fear Inhibition during a Vulnerable Period of Development.

Authors:  Kelsey S Zimmermann; Rick Richardson; Kathryn D Baker
Journal:  Brain Sci       Date:  2019-03-18
  10 in total
  1 in total

1.  Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus.

Authors:  Marie-Gabrielle Goossens; Lars Emil Larsen; Marijke Vergaelen; Wytse Wadman; Chris Van den Haute; Wayra Brackx; Silke Proesmans; Jana Desloovere; Emma Christiaen; Erine Craey; Christian Vanhove; Kristl Vonck; Paul Boon; Robrecht Raedt
Journal:  eNeuro       Date:  2021-11-04
  1 in total

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