Harm-Jan de Grooth1,2, Pieter R Tuinman3, Armand R J Girbes3. 1. Department of Intensive Care, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. h.degrooth@amsterdamumc.nl. 2. Department of Anesthesiology, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, Amsterdam, The Netherlands. h.degrooth@amsterdamumc.nl. 3. Department of Intensive Care, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.