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Literature DB >> 3233792

Lymphoid immunohistochemistry of macaque primates.

L D Ormerod¹, K G Osborn, L J Lowenstine, P R Meyer, J W Parker, R E Smith, C R Taylor.

Abstract

The immunohistochemical localizations of 53 monoclonal antibodies with specificities expressed in human lymphoid tissue were investigated on lymph node tissues from Macaca mulatta, M. speciosa, and M. fascicularis using immunoperoxidase techniques. Thirty antibodies showed comparative cross-reactivity. The micro-anatomic distribution of these antigens was closely homologous to that observed in man and antigen densities appeared to be similar. A useful monoclonal antibody panel for immunopathological investigations in macaques was, thereby, defined. Of several pan-T antibodies studied, only OKT11(CD2) showed cross-reactivity. A detailed analysis of the immunocyto-architecture of five rhesus lymph nodes was undertaken. Automated flow cytometry of M. mulatta and M. speciosa peripheral blood showed a broadly similar pattern to man.

Entities: Gene Species

Mesh：

Substances：

Year: 1988 PMID： 3233792 PMCID： PMC1542026

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

25 in total

1. Analysis of lymphoid and dendritic cells in human lymph node, tonsil and spleen. A study using monoclonal and heterologous antibodies.

Authors: P van der Valk; E M van der Loo; J Jansen; M R Daha; C J Meijer
Journal: Virchows Arch B Cell Pathol Incl Mol Pathol Date: 1984

2. Distribution of B lymphocyte subsets in normal lymphoid tissue.

Authors: L J Murray; S H Swerdlow; J A Habeshaw
Journal: Clin Exp Immunol Date: 1984-05 Impact factor: 4.330

3. Immunohistological localization of human lymphocyte subsets.

Authors: R Giorno; P F Kohler
Journal: Diagn Immunol Date: 1983

4. Phenotypic expression of B-lymphocytes. 2. Immunoglobulin expression of germinal center cells.

Authors: S M Hsu; E S Jaffe
Journal: Am J Pathol Date: 1984-03 Impact factor: 4.307

5. Immunohistochemical localization of cells reacting with monoclonal antibodies directed against the interleukin-2 receptor of murine, rat and human origin.

Authors: L Takacs; H Osawa; I Törö; T Diamantstein
Journal: Clin Exp Immunol Date: 1985-01 Impact factor: 4.330

6. Delineation of lymphocyte subsets in lymph nodes of nonhuman primates.

Authors: L V Chalifoux; S F Schlossman; N L Letvin
Journal: Clin Immunol Immunopathol Date: 1984-04

7. Distribution of antigens defined by OKB monoclonal antibodies on benign and malignant lymphoid cells and on nonlymphoid tissues.

Authors: D M Knowles; B Tolidjian; C C Marboe; R S Mittler; M A Talle; G Goldstein
Journal: Blood Date: 1984-04 Impact factor: 22.113

Lymphoid immunohistochemistry of macaque primates.

1. Analysis of lymphoid and dendritic cells in human lymph node, tonsil and spleen. A study using monoclonal and heterologous antibodies.

2. Distribution of B lymphocyte subsets in normal lymphoid tissue.

3. Immunohistological localization of human lymphocyte subsets.

4. Phenotypic expression of B-lymphocytes. 2. Immunoglobulin expression of germinal center cells.

5. Immunohistochemical localization of cells reacting with monoclonal antibodies directed against the interleukin-2 receptor of murine, rat and human origin.

6. Delineation of lymphocyte subsets in lymph nodes of nonhuman primates.

7. Distribution of antigens defined by OKB monoclonal antibodies on benign and malignant lymphoid cells and on nonlymphoid tissues.

8. Immunohistologic localization and immune phenotypes of lymphocytes expressing Tac antigen in human lymphoid tissues.

9. Evolution of epitopes on human and nonhuman primate lymphocyte cell surface antigens.

10. Heterogeneity of macrophage populations in human lymphoid tissue and peripheral blood.

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