| Literature DB >> 32337766 |
Caner Süsal1, Gizem Kumru1, Bernd Döhler1, Christian Morath2, Marije Baas3, Jens Lutz4, Christian Unterrainer1, Wolfgang Arns5, Olivier Aubert6, Christoph Bara7, Andres Beiras-Fernandez8, Georg A Böhmig9, Claudia Bösmüller10, Fritz Diekmann11, Philipp Dutkowski12, Ingeborg Hauser13, Christophe Legendre6, Vladimir J Lozanovski14, Arianeb Mehrabi14, Anette Melk15, Thomas Minor16, Thomas F Mueller17, Przemyslaw Pisarski18, Lionel Rostaing19, Peter Schemmer20, Stefan Schneeberger9, Vedat Schwenger21, Claudia Sommerer2, Burkhard Tönshoff22, Richard Viebahn23, Ondrej Viklicky24, Rolf Weimer25, Karl-Heinz Weiss26, Martin Zeier2, Stela Živčić-Ćosić27, Uwe Heemann28.
Abstract
In several deceased donor kidney allocation systems, organs from elderly donors are allocated primarily to elderly recipients. The Eurotransplant Senior Program (ESP) was implemented in 1999, and since then, especially in Europe, the use of organs from elderly donors has steadily increased. The proportion of ≥60-year-old donors reported to the Collaborative Transplant Study (CTS) by European centers has doubled, from 21% in 2000-2001 to 42% in 2016-2017. Therefore, in the era of organ shortage it is a matter of debate whether kidney organs from elderly donors should only be allocated to elderly recipients or whether <65-year-old recipients can also benefit from these generally as "marginal" categorized organs. To discuss this issue, a European Consensus Meeting was organized by the CTS on April 12, 2018, in Heidelberg, in which 36 experts participated. Based on available evidence, it was unanimously concluded that kidney organs from 65- to 74-year-old donors can also be allocated to 55- to 64-year-old recipients, especially if these organs are from donors with no history of hypertension, no increased creatinine, no cerebrovascular death, and no other reasons for defining a marginal donor, such as diabetes or cancer.Entities:
Keywords: donation; expanded donor pool; kidney clinical; outcome
Year: 2020 PMID: 32337766 DOI: 10.1111/tri.13628
Source DB: PubMed Journal: Transpl Int ISSN: 0934-0874 Impact factor: 3.782