Literature DB >> 3233772

Accurate and specific HPLC assay of coproporphyrinogen III oxidase activity in human peripheral leucocytes.

R Guo1, C K Lim, T J Peters.   

Abstract

An HPLC method is described for the assay of coproporphyrinogen III oxidase in human leucocytes. The optimal pH for the assay was 6.5-7.0 and the Km for coproporphyrinogen III was 0.12 +/- 0.021 mumol/l. The mean activity in 28 apparently health subjects was 0.249 (2 SD range 0.130-0.368) nmol/h per mg protein. In two patients with hereditary coproporphyria, the activities were 0.029 and 0.078 nmol/h per mg protein.

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Year:  1988        PMID: 3233772     DOI: 10.1016/0009-8981(88)90069-1

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN: 0009-8981            Impact factor:   3.786


  4 in total

1.  A description of an HPLC assay of coproporphyrinogen III oxidase activity in mononuclear cells.

Authors:  U Gross; R Gerlach; A Kühnel; V Seifert; M O Doss
Journal:  J Inherit Metab Dis       Date:  2003       Impact factor: 4.982

2.  Laparoscopic fluorescence diagnosis for intraabdominal fluorescence targeting of peritoneal carcinosis experimental studies.

Authors:  Johannes Gahlen; Ruediger L Prosst; Matthias Pietschmann; Thomas Haase; Markus Rheinwald; Gisela Skopp; Josef Stern; Christian Herfarth
Journal:  Ann Surg       Date:  2002-02       Impact factor: 12.969

Review 3.  Environmental chemical exposures and disturbances of heme synthesis.

Authors:  W E Daniell; H L Stockbridge; R F Labbe; J S Woods; K E Anderson; D M Bissell; J R Bloomer; R D Ellefson; M R Moore; C A Pierach; W E Schreiber; A Tefferi; G M Franklin
Journal:  Environ Health Perspect       Date:  1997-02       Impact factor: 9.031

Review 4.  D-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders.

Authors:  Herman Wolosker; Darrick T Balu
Journal:  Transl Psychiatry       Date:  2020-06-09       Impact factor: 6.222

  4 in total

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