Literature DB >> 32337110

Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis.

Michael R Goetsch1, Jeffrey Shen2, Jeffrey A Jones3, Adeel Memon4, Walter Chatham5.   

Abstract

Neuralgic amyotrophy (NA), also known as Parsonage-Turner syndrome, is an idiopathic disorder characterized by rapid-onset unilateral upper extremity pain, paralysis, and sensory disturbance in the distribution of the brachial plexus. The etiology is unknown, and there is a multitude of alternative clinical presentations as well as secondary triggers, which make the diagnosis challenging. To date, there has been no report of NA presenting with frank myonecrosis. In this report, we document the first case of NA presenting with multifocal myonecrosis of the shoulder girdle muscles and rhabdomyolysis. This case posed a unique challenge in the diagnostic workup and management as many causes of myonecrosis present similarly to NA, and NA is a diagnosis of exclusion. Our patient underwent exhaustive testing and several trials of therapy before diagnosis could be made. Such evaluations are expensive and carry risks for patients. As such, it is important that physicians recognize this unique presentation of NA.
Copyright © 2020, Goetsch et al.

Entities:  

Keywords:  brachial neuritis; brachial plexitis; brachial plexopathy; myonecrosis; neuralgic amyotrophy; neuropathy; parsonage turner syndrome; rhabdomyolysis; shoulder girdle

Year:  2020        PMID: 32337110      PMCID: PMC7179979          DOI: 10.7759/cureus.7382

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  20 in total

1.  High dose intravenous immune globulin in the treatment of hereditary recurrent brachial plexus neuropathy.

Authors:  G Ardolino; S Barbieri; A Priori
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-04       Impact factor: 10.154

2.  Partial but rapid recovery from paralysis after immunomodulation during early stage of neuralgic amyotrophy.

Authors:  Masashi Nakajima; Shinsuke Fujioka; Hideki Ohno; Kohnosuke Iwamoto
Journal:  Eur Neurol       Date:  2006-06-14       Impact factor: 1.710

3.  The clinical spectrum of neuralgic amyotrophy in 246 cases.

Authors:  Nens van Alfen; Baziel G M van Engelen
Journal:  Brain       Date:  2005-12-21       Impact factor: 13.501

4.  Natural history of brachial plexus neuropathy. Report on 99 patients.

Authors:  P Tsairis; P J Dyck; D W Mulder
Journal:  Arch Neurol       Date:  1972-08

Review 5.  Clinical and pathophysiological concepts of neuralgic amyotrophy.

Authors:  Nens van Alfen
Journal:  Nat Rev Neurol       Date:  2011-05-10       Impact factor: 42.937

6.  Four cases of anti-ganglioside antibody-positive neuralgic amyotrophy with good response to intravenous immunoglobulin infusion therapy.

Authors:  Kota Moriguchi; Katsuichi Miyamoto; Kazuo Takada; Susumu Kusunoki
Journal:  J Neuroimmunol       Date:  2011-08-27       Impact factor: 3.478

7.  Parsonage-Turner syndrome: MR imaging findings and clinical information of 27 patients.

Authors:  Cree M Gaskin; Clyde A Helms
Journal:  Radiology       Date:  2006-08       Impact factor: 11.105

8.  MRI findings of 26 patients with Parsonage-Turner syndrome.

Authors:  Richard E Scalf; Doris E Wenger; Matthew A Frick; Jayawant N Mandrekar; Mark C Adkins
Journal:  AJR Am J Roentgenol       Date:  2007-07       Impact factor: 3.959

Review 9.  Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis).

Authors:  Nens van Alfen; Baziel G M van Engelen; Richard A C Hughes
Journal:  Cochrane Database Syst Rev       Date:  2009-07-08

10.  Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis.

Authors:  G A Suarez; C Giannini; E P Bosch; R J Barohn; J Wodak; P Ebeling; R Anderson; P E McKeever; M B Bromberg; P J Dyck
Journal:  Neurology       Date:  1996-02       Impact factor: 9.910

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