Ying Dai1, Guanyang Lin1, Dawei Shi2. 1. Department of Pharmacy, First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, China. 2. Department of Pharmacy, First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, China. Electronic address: shidawei800@126.com.
Abstract
PURPOSE: Several case reports have highlighted symptomatic hypoglycemia as a serious but uncommon adverse effect of hydroxychloroquine (HCQ) in nondiabetic subjects. METHODS: This study describes a nondiabetic patient who experienced serious hypoglycemia related to HCQ. FINDINGS: In the course of treatment, the patient experienced multiple episodes of hypoglycemia at night and in the early morning. The hypoglycemia was usually accompanied by nausea, fatigue, and dizziness. The lowest value of blood glucose in the fingertip was 2.6 mmol/L. IMPLICATIONS: This rare case will prompt clinicians to pay attention to unexplained hypoglycemia when using HCQ in nondiabetic patients.
PURPOSE: Several case reports have highlighted symptomatic hypoglycemia as a serious but uncommon adverse effect of hydroxychloroquine (HCQ) in nondiabetic subjects. METHODS: This study describes a nondiabetic patient who experienced serious hypoglycemia related to HCQ. FINDINGS: In the course of treatment, the patient experienced multiple episodes of hypoglycemia at night and in the early morning. The hypoglycemia was usually accompanied by nausea, fatigue, and dizziness. The lowest value of blood glucose in the fingertip was 2.6 mmol/L. IMPLICATIONS: This rare case will prompt clinicians to pay attention to unexplained hypoglycemia when using HCQ in nondiabetic patients.
Authors: Ioannis Ilias; Edison Jahaj; Stylianos Kokkoris; Dimitrios Zervakis; Prodromos Temperikidis; Eleni Magira; Maria Pratikaki; Alice G Vassiliou; Christina Routsi; Anastasia Kotanidou; Ioanna Dimopoulou Journal: In Vivo Date: 2020 Sep-Oct Impact factor: 2.155
Authors: Abu Saleh Md Moin; Ahmed Al-Qaissi; Thozhukat Sathyapalan; Stephen L Atkin; Alexandra E Butler Journal: Front Endocrinol (Lausanne) Date: 2021-06-23 Impact factor: 5.555