| Literature DB >> 32336414 |
Eric Deconinck1, Tony Petrella2, Francine Garnache Ottou3.
Abstract
Clinical and biological presentation of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) is depicted to highlight criteria that might alert physicians. Diagnosis of BPDCN is still challenging and requires (1) immunophenotyping of blood or bone marrow aspiration using several markers (CD4, CD56, HLA-DR, myeloid and lymphoid lineage markers) and should include pDC markers such as CD123, cTCL1, CD303, and CD304, and/or (2) pathologic analysis of cutaneous lesions, also with immunohistochemistry using markers specific to BPDCN. CrownEntities:
Keywords: Anatomopathology; BPDCN; Clinical presentation; Diagnosis; Immunophenotyping; Morphologies
Year: 2020 PMID: 32336414 DOI: 10.1016/j.hoc.2020.01.010
Source DB: PubMed Journal: Hematol Oncol Clin North Am ISSN: 0889-8588 Impact factor: 3.722