Literature DB >> 32333219

Comparison of CT-based and MRI-based high-risk clinical target volumes in image guided-brachytherapy for cervical cancer, referencing recommendations from the Japanese Radiation Oncology Study Group (JROSG) and consensus statement guidelines from the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC ESTRO).

Yuma Iwai1, Miho Watanabe Nemoto2, Takuro Horikoshi2, Aki Kanazawa2, Marie Kurokawa2, Makoto Saito2, Rintaro Harada2, Hiroki Kobayashi2, Takashi Uno2.   

Abstract

PURPOSE: The Working Group of the Gynecological Tumor Committee of the Japanese Radiation Oncology Study Group (JROSG) published recommendations for contouring high-risk clinical target volumes (HR-CTV) on CT for 3-dimentional image-guided brachytherapy for cervical cancer. The purpose of this study was to compare HR-CTV delineated on CT, referencing recommendations from JROSG, with HR-CTV delineated on MRI, referencing consensus guidelines from the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC ESTRO).
MATERIAL AND METHODS: Fourteen patients were evaluated. After the insertion of the CT/MR applicator into the patient, CT and MRI were performed. HR-CTVMR was delineated on MRI for clinical examination and HR-CTVCT was delineated on CT retrospectively referencing the MRI just before brachytherapy within a week. The volume and dosimetry of HR-CTV based on a 6 Gy dose of the Manchester system were evaluated.
RESULTS: The median volumes of HR-CTVMR and HR-CTVCT were 24.4 ml (range, 13.6-50.4 ml) and 29.9 ml (range, 13.2-49.2 ml), respectively. Median D90 of HR-CTVMR and HR-CTVCT were 6.7 Gy (range, 5.8-10.1 Gy) and 6.8 Gy (range, 5.1-10.4 Gy), respectively.
CONCLUSION: Somewhat difference could be seen between HR-CTVMR and HR-CTVCT.

Entities:  

Keywords:  Cervical cancer; High-risk clinical target volume; Image-guided brachytherapy; MRI

Mesh:

Year:  2020        PMID: 32333219     DOI: 10.1007/s11604-020-00980-y

Source DB:  PubMed          Journal:  Jpn J Radiol        ISSN: 1867-1071            Impact factor:   2.374


  1 in total

1.  Dose-effect relationship between dose-volume parameters of residual gross tumor volume and clinical prognosis in MRI-guided adaptive brachytherapy for locally advanced cervical cancer: a single-center retrospective study.

Authors:  Tianyang Ke; Jinbao Wang; Ning Zhang; Hongfu Zhao; Xin Guo; Zhipeng Zhao; Zhuang Mao; Guanghui Cheng
Journal:  Strahlenther Onkol       Date:  2022-09-15       Impact factor: 4.033

  1 in total

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