| Literature DB >> 32329338 |
Min Yang1, Jing Chen1, Chen He1, Xin Hu1, Yechun Ding1, Ying Kuang1, Jinbiao Liu2, Qitong Huang1.
Abstract
An alternative process of Pd-catalyzed C-4 selective coupling of 2,4-dichloropyridines with boronic esters was developed, which afforded 24 examples of C-4 coupled pyridines in moderate to good yields. After further arylation, 21 examples of C-2, C-4 diarylated pyridines with a significant photophysical property were obtained, which were applied as pyridine-based dyes into live-cell imaging with good biocompatibility and low toxicity.Entities:
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Year: 2020 PMID： 32329338 DOI： 10.1021/acs.joc.0c00449
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354