Literature DB >> 32327457

Supraclavicular left neck mass: an unusual presentation of metastatic testicular cancer in two older men.

Chinnoi Law1, Zainab AlshiekhAli2, Nicholas Taylor3, David Howlett4.   

Abstract

Two male patients, aged 55 and 75 years, were referred to the ENT and haematology team respectively, with an asymptomatic left supraclavicular neck mass. Investigations revealed metastatic primary testicular seminoma. CT contrast study of the thorax, abdomen and pelvis demonstrated an additional left para-aortic nodal mass in both cases. The initial presentation of a solitary left neck lump from a metastatic testicular seminoma is extremely unusual, especially in an older age group. The pattern of metastatic spread to the supraclavicular neck nodes from a single para-aortic lymph node is also an interesting finding. Although the majority of seminomas present in younger patients in the early stages when confined to the testis, seminoma can also occur in older patients and can present in an atypical manner. The ability to recognise an atypical presentation in an older patient is invaluable for prompt diagnosis, treatment and follow-up of disease. This case also highlights the importance of a multisystematic structured and an open-minded approach to investigating and diagnosing a neck mass. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  ear, nose and throat/otolaryngology; radiology; urological cancer

Mesh:

Substances:

Year:  2020        PMID: 32327457      PMCID: PMC7202787          DOI: 10.1136/bcr-2019-233368

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

1.  Blood group-related antigens in human germ cell tumors.

Authors:  R J Motzer; V E Reuter; C Cordon-Cardo; G J Bosl
Journal:  Cancer Res       Date:  1988-09-15       Impact factor: 12.701

2.  Cervical lymph node dissection for metastatic testicular cancer.

Authors:  M G van Vledder; J A van der Hage; W J Kirkels; J W Oosterhuis; C Verhoef; J H W de Wilt
Journal:  Ann Surg Oncol       Date:  2010-03-24       Impact factor: 5.344

3.  Testicular seminoma: a clinicopathologic and immunohistochemical study of 105 cases with special reference to seminomas with atypical features.

Authors:  Satish K Tickoo; Brian Hutchinson; Jennifer Bacik; Madhu Mazumdar; Robert J Motzer; Dean F Bajorin; George J Bosl; Victor E Reuter
Journal:  Int J Surg Pathol       Date:  2002-01       Impact factor: 1.271

4.  Metastatic testicular seminoma--a case report.

Authors:  Rajiv K Bhalla; Terence M Jones; Doug Errington; Nicholas J Roland
Journal:  Auris Nasus Larynx       Date:  2002-04       Impact factor: 1.863

5.  Prognostic features and markers for testicular cancer management.

Authors:  Eddy S Leman; Mark L Gonzalgo
Journal:  Indian J Urol       Date:  2010 Jan-Mar

6.  Metastatic seminoma with cervical lymphadenopathy as the initial manifestation.

Authors:  Lee M Akst; Christopher Discolo; Bruno Dipasquale; David Greene; Jay Roberts
Journal:  Ear Nose Throat J       Date:  2004-05       Impact factor: 1.697

7.  Lymphatic mapping and gamma probe guided laparoscopic biopsy of sentinel lymph node in patients with clinical stage I testicular tumor.

Authors:  Chikara Ohyama; Yutaka Chiba; Tetsuro Yamazaki; Mareyuki Endoh; Senji Hoshi; Yoichi Arai
Journal:  J Urol       Date:  2002-10       Impact factor: 7.450

8.  Changes in epidemiologic features of testicular germ cell cancer: age at diagnosis and relative frequency of seminoma are constantly and significantly increasing.

Authors:  Christian G Ruf; Hendrik Isbarn; Walter Wagner; Margit Fisch; Cord Matthies; Klaus-Peter Dieckmann
Journal:  Urol Oncol       Date:  2013-02-06       Impact factor: 3.498

9.  Testicular Germ-Cell Tumours: A Descriptive Analysis of Clinical Characteristics at First Presentation.

Authors:  Klaus-Peter Dieckmann; Hanna Richter-Simonsen; Magdalena Kulejewski; Raphael Ikogho; Henrik Zecha; Petra Anheuser; Uwe Pichlmeier; Hendrik Isbarn
Journal:  Urol Int       Date:  2018-04-12       Impact factor: 2.089

10.  Patterns of supradiaphragmatic metastases in testicular germ cell tumours.

Authors:  A Wood; N Robson; K Tung; G Mead
Journal:  Clin Radiol       Date:  1996-04       Impact factor: 2.350

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