Ahmed Arafa1,2, Jia-Yi Dong1. 1. Department of Public Health, Graduate School of Medicine, Osaka University , Osaka, Japan. 2. Department of Public Health, Faculty of Medicine, Beni-Suef University , Beni-Suef, Egypt.
Abstract
OBJECTIVE: To investigate the association between intrahepatic cholestasis of pregnancy (ICP) and the risk of gestational diabetes mellitus (GDM) and preeclampsia via meta-analysis. METHODS: Pooled odds ratio (OR) and confidence interval (CI) of GDM and preeclampsia for women with ICP were calculated using the fixed- or random-effects model. RESULTS: Women with ICP were more likely to have GDM (pooled OR = 2.19, 95% CI: 1.58, 3.03, I 2 = 88.25%) and preeclampsia (pooled OR = 2.58, 95% CI: 2.37, 2.81, I 2 = 0%) than women without ICP. CONCLUSION: The present study supports the concept that ICP is associated with the risk of GDM and preeclampsia.
OBJECTIVE: To investigate the association between intrahepatic cholestasis of pregnancy (ICP) and the risk of gestational diabetes mellitus (GDM) and preeclampsia via meta-analysis. METHODS: Pooled odds ratio (OR) and confidence interval (CI) of GDM and preeclampsia for women with ICP were calculated using the fixed- or random-effects model. RESULTS:Women with ICP were more likely to have GDM (pooled OR = 2.19, 95% CI: 1.58, 3.03, I 2 = 88.25%) and preeclampsia (pooled OR = 2.58, 95% CI: 2.37, 2.81, I 2 = 0%) than women without ICP. CONCLUSION: The present study supports the concept that ICP is associated with the risk of GDM and preeclampsia.
Entities:
Keywords:
Intrahepatic cholestasis of pregnancy; gestational diabetes; meta-analysis; preeclampsia
Authors: Nazan Yurtcu; Canan Soyer Caliskan; Huri Guvey; Samettin Celik; Safak Hatirnaz; Andrea Tinelli Journal: Int J Environ Res Public Health Date: 2022-02-16 Impact factor: 3.390
Authors: Carsten Hagenbeck; Ulrich Pecks; Frank Lammert; Matthi As C Hütten; Felix Borgmeier; Tanja Fehm; Ekkehard Schleußner; Holger Maul; Sven Kehl; Amr Hamza; Verena Keitel Journal: Gynakologe Date: 2021-04-20
Authors: Huri Güvey; Samettin Çelik; Canan Soyer Çalışkan; Zehra Yılmaz; Merve Yılmaz; Özlem Erten; Andrea Tinelli Journal: Int J Environ Res Public Health Date: 2021-11-29 Impact factor: 3.390