Literature DB >> 32325059

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.

Jone López-Erauskin, Takahiro Tadokoro, Michael W Baughn, Brian Myers, Melissa McAlonis-Downes, Carlos Chillon-Marinas, Joshua N Asiaban, Jonathan Artates, Anh T Bui, Anne P Vetto, Sandra K Lee, Ai Vy Le, Ying Sun, Mélanie Jambeau, Jihane Boubaker, Deborah Swing, Jinsong Qiu, Geoffrey G Hicks, Zhengyu Ouyang, Xiang-Dong Fu, Lino Tessarollo, Shuo-Chien Ling, Philippe A Parone, Christopher E Shaw, Martin Marsala, Clotilde Lagier-Tourenne, Don W Cleveland, Sandrine Da Cruz.   

Abstract

Entities:  

Year:  2020        PMID: 32325059      PMCID: PMC7184958          DOI: 10.1016/j.neuron.2020.04.006

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


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(Neuron 100, 816–830.e1–e7; November 21, 2018) In the original publication of this paper, the concentration of the puromycin was incorrectly reported. In both panel A of Figure 7 and the “In vivo protein synthesis labeling” section of the STAR Methods, the amount was listed as 10 μg/kg. The correct concentration should be 10 mg/kg. The authors apologize for this error.
  4 in total

Review 1.  Transportin-1: A Nuclear Import Receptor with Moonlighting Functions.

Authors:  Allegra Mboukou; Vinod Rajendra; Renata Kleinova; Carine Tisné; Michael F Jantsch; Pierre Barraud
Journal:  Front Mol Biosci       Date:  2021-02-18

Review 2.  The Interplay of RNA Binding Proteins, Oxidative Stress and Mitochondrial Dysfunction in ALS.

Authors:  Jasmine Harley; Benjamin E Clarke; Rickie Patani
Journal:  Antioxidants (Basel)       Date:  2021-04-02

3.  TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain.

Authors:  Jasmine Harley; Cathleen Hagemann; Andrea Serio; Rickie Patani
Journal:  Brain Commun       Date:  2021-08-06

Review 4.  Dysfunction of RNA/RNA-Binding Proteins in ALS Astrocytes and Microglia.

Authors:  Simona Rossi; Mauro Cozzolino
Journal:  Cells       Date:  2021-11-03       Impact factor: 6.600

  4 in total

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