Literature DB >> 32322476

Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report.

A Juneja1, A Sultan1, S Iqbal2.   

Abstract

Simultaneous presentation of tuberculosis (TB) and lymphoma in a young child is indeed a very rare entity. Malignancy such as Hodgkin's disease (HD) most commonly causes suppression of the cell-mediated immunity, which makes the individual, especially children, more prone to tuberculous infection. One of the non-life threatening complications in these young cancer survivors is the associated dental anomalies. These can seriously impair the quality of life of teenagers and young adults. Higher incidence of caries, discoloration of teeth or even early loss of teeth requiring dental prosthesis, can be associated with the use of cytostatic drugs. These drugs can also disturb odontogenesis, resulting in the absence of tooth buds, microdontia, dilacerations or shortening of tooth roots. Some of the anticancer drugs, including busulfan, cyclophosphamide, doxorubicin etc. May particularly play a significant role in the development of dental anomalies. This paper is a short review and case report of an 11 year old child having oligodontia and secondary dental complications caused as a side effect of treatment of Hodgkin's lymphoma with Tuberculous Lymphadenitis.
© 2020 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Anomalies; Drugs; Hodgkins lymphoma; Tooth agenesis; Tuberculous

Year:  2020        PMID: 32322476      PMCID: PMC7163057          DOI: 10.1016/j.jobcr.2020.04.002

Source DB:  PubMed          Journal:  J Oral Biol Craniofac Res        ISSN: 2212-4268


  9 in total

1.  A scanning electron microscopy study of disturbances in the developing rat molar induced by cyclophosphamide.

Authors:  M Näsman; K Hultenby; C M Forsberg
Journal:  Acta Odontol Scand       Date:  1997-06       Impact factor: 2.331

Review 2.  Dental abnormalities of a long-term survivor of a childhood hematological malignancy: literature review and report of a case.

Authors:  R S Raja Zarina; N N Nik-Hussein
Journal:  J Clin Pediatr Dent       Date:  2005       Impact factor: 1.065

Review 3.  PAX9 gene mutations and tooth agenesis: A review.

Authors:  O Bonczek; V J Balcar; O Šerý
Journal:  Clin Genet       Date:  2017-03-30       Impact factor: 4.438

4.  Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes.

Authors:  Birgitta Bergendal; Joakim Klar; Christina Stecksén-Blicks; Johanna Norderyd; Niklas Dahl
Journal:  Am J Med Genet A       Date:  2011-05-27       Impact factor: 2.802

5.  Influence of the antineoplastic agent cyclophosphamide on dental development in rat molars.

Authors:  M Näsman; L Hammarström
Journal:  Acta Odontol Scand       Date:  1996-10       Impact factor: 2.331

6.  Dental and maxillofacial abnormalities in long-term survivors of childhood cancer: effects of treatment with chemotherapy and radiation to the head and neck.

Authors:  N Jaffe; B B Toth; R E Hoar; H L Ried; M P Sullivan; M D McNeese
Journal:  Pediatrics       Date:  1984-06       Impact factor: 7.124

7.  Simultaneous occurrence of Hodgkin's disease and tubercular lymphadenitis in the same cervical lymph node: a rare presentation.

Authors:  Kunal Mahajan; Gunjan Gupta; Davinder Pal Singh; Aditi Mahajan
Journal:  BMJ Case Rep       Date:  2016-01-06

8.  Dental Anomalies as Late Adverse Effect among Young Children Treated for Cancer.

Authors:  Patrycja Proc; Joanna Szczepańska; Adam Skiba; Małgorzata Zubowska; Wojciech Fendler; Wojciech Młynarski
Journal:  Cancer Res Treat       Date:  2015-10-14       Impact factor: 4.679

9.  Long-term Dental Anomalies after Pediatric Cancer Treatment in Children

Authors:  Gülser Kılınç; Gülçin Bulut; Fahinur Ertuğrul; Hale Ören; Bengü Demirağ; Ayşe Demiral; Serap Aksoylar; Emine Serra Kamer; Hülya Ellidokuz; Nur Olgun
Journal:  Turk J Haematol       Date:  2018-10-16       Impact factor: 1.831

  9 in total

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