Literature DB >> 32320844

Protocol for an embedded pragmatic clinical trial to test the effectiveness of Aliviado Dementia Care in improving quality of life for persons living with dementia and their informal caregivers.

Alycia A Bristol1, Kimberly A Convery2, Victor Sotelo2, Catherine E Schneider1, Shih-Yin Lin1, Jason Fletcher1, Randall Rupper3, James E Galvin4, Abraham A Brody5.   

Abstract

INTRODUCTION: Persons living with Alzheimer's disease and related dementias (ADRD) frequently experience pain and behavioral and psychological symptoms of dementia (BPSD) which decrease quality of life (QOL) and influence caregiver burden. Home healthcare professionals however may underrecognize or lack the ability to manage BPSD. INTERVENTION: This protocol describes an ADRD palliative quality assurance performance improvement program for home healthcare, Aliviado Dementia Care-Home Health Edition. It includes training, mentoring, and a toolbox containing intervention strategies.
METHODS: This embedded pragmatic clinical trial will utilize a multi-site, cluster randomized control design. Recruitment will occur from three home healthcare agencies located in New Jersey, Utah, and Florida. At each agency, care teams will be randomized as clusters and assigned to either the Aliviado Dementia Care program or usual care. We plan to enroll 345 persons living with ADRD and their informal caregiver dyads. The primary outcome will be to measure QOL in both the person living with ADRD and their informal caregiver, and emergency department visits and hospital admissions. Secondary outcomes in the person living with ADRD will include the examination of pain, BPSD, antipsychotic and analgesic use. Secondary outcomes in caregivers include burden, depressive symptoms, functional health and wellbeing, and healthcare utilization.
CONCLUSION: This study will be the first large-scale embedded pragmatic clinical trial in home healthcare focused on care quality and outcomes in addressing QOL in ADRD. If proven successful, the intervention can then be disseminated to agencies throughout the country to improve the quality of care for this vulnerable, underserved population. TRIAL REGISTRATION: Clinical Trials.gov: NCT03255967.
Copyright © 2020. Published by Elsevier Inc.

Entities:  

Keywords:  Behavioral and psychological symptoms of dementia; Dementia; Home healthcare; Informal caregivers; Pragmatic clinical trial; Quality of life

Year:  2020        PMID: 32320844      PMCID: PMC7269690          DOI: 10.1016/j.cct.2020.106005

Source DB:  PubMed          Journal:  Contemp Clin Trials        ISSN: 1551-7144            Impact factor:   2.226


  49 in total

1.  Assessment and measurement of pain in older adults.

Authors:  K A Herr; L Garand
Journal:  Clin Geriatr Med       Date:  2001-08       Impact factor: 3.076

Review 2.  The management of persistent pain in older persons.

Authors: 
Journal:  J Am Geriatr Soc       Date:  2002-06       Impact factor: 5.562

3.  Assessment of capacity to consent to research among older persons with schizophrenia, Alzheimer disease, or diabetes mellitus: comparison of a 3-item questionnaire with a comprehensive standardized capacity instrument.

Authors:  Barton W Palmer; Laura B Dunn; Paul S Appelbaum; Sunder Mudaliar; Leon Thal; Robert Henry; Shahrokh Golshan; Dilip V Jeste
Journal:  Arch Gen Psychiatry       Date:  2005-07

4.  Quality of Hospice Care at Home Versus in an Assisted Living Facility or Nursing Home.

Authors:  Kathleen T Unroe; Timothy E Stump; Shannon Effler; Wanzhu Tu; Christopher M Callahan
Journal:  J Am Geriatr Soc       Date:  2018-02-10       Impact factor: 5.562

5.  Use of a self-report-generated Charlson Comorbidity Index for predicting mortality.

Authors:  Saima Chaudhry; Lei Jin; David Meltzer
Journal:  Med Care       Date:  2005-06       Impact factor: 2.983

6.  The impact of post-operative pain on outcomes following hip fracture.

Authors:  Sean R Morrison; Jay Magaziner; Mary Ann McLaughlin; Gretchen Orosz; Stacey B Silberzweig; Kenneth J Koval; Albert L Siu
Journal:  Pain       Date:  2003-06       Impact factor: 6.961

Review 7.  Elderly patients with dementia-related symptoms of severe agitation and aggression: consensus statement on treatment options, clinical trials methodology, and policy.

Authors:  Carl Salzman; Dilip V Jeste; Roger E Meyer; Jiska Cohen-Mansfield; Jeffrey Cummings; George T Grossberg; Lissy Jarvik; Helena C Kraemer; Barry D Lebowitz; Katie Maslow; Bruce G Pollock; Murray Raskind; Susan K Schultz; Philip Wang; Julie M Zito; George S Zubenko
Journal:  J Clin Psychiatry       Date:  2008-06       Impact factor: 4.384

8.  Care Settings and Clinical Characteristics of Older Adults with Moderately Severe Dementia.

Authors:  Krista L Harrison; Christine S Ritchie; Kanan Patel; Lauren J Hunt; Kenneth E Covinsky; Kristine Yaffe; Alexander K Smith
Journal:  J Am Geriatr Soc       Date:  2019-08-07       Impact factor: 5.562

Review 9.  A review of age differences in the neurophysiology of nociception and the perceptual experience of pain.

Authors:  Stephen J Gibson; Michael Farrell
Journal:  Clin J Pain       Date:  2004 Jul-Aug       Impact factor: 3.442

10.  THE QUICK DEMENTIA RATING SYSTEM (QDRS): A RAPID DEMENTIA STAGING TOOL.

Authors:  James E Galvin
Journal:  Alzheimers Dement (Amst)       Date:  2015-06-01
View more
  1 in total

1.  Aliviado Mobile App for Hospice Providers: A Usability Study.

Authors:  Daniel David; Shih-Yin Lin; Lisa L Groom; Ariel Ford; Abraham A Brody
Journal:  J Pain Symptom Manage       Date:  2021-08-10       Impact factor: 3.612

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.