Literature DB >> 32320766

Cutaneous adverse reactions to anti-PD-1 treatment-A systematic review.

Anne Birgitte Simonsen1, Jeanette Kaae2, Eva Ellebaek3, Inge Marie Svane3, Claus Zachariae2.   

Abstract

The use of the humanized monoclonal anti-programmed cell death 1 antibodies pembrolizumab and nivolumab as potent anticancer therapies is rapidly increasing. However, since their approval, numerous cases of cutaneous reactions have been reported. Cutaneous adverse reactions to these agents have yet to be fully characterized and range from nonspecific eruptions to recognizable skin manifestations, which may be localized and vary from mild to life threatening. This systematic review article provides an overview of the various adverse cutaneous reactions to pembrolizumab and nivolumab therapy and offers suggestions for their management.
Copyright © 2020 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  anti–PD-1; cutaneous adverse reaction; dermatology; immunotherapy; oncology

Mesh：

Substances：

Year:  2020        PMID： 32320766     DOI： 10.1016/j.jaad.2020.04.058

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN： 0190-9622            Impact factor:   11.527


  4 in total

1.  Steven-Johnson Syndrome: A Rare but Serious Adverse Event of Nivolumab Use in a Patient With Metastatic Gastric Adenocarcinoma.

Authors:  Eltaib Saad; Pabitra Adhikari; Drashti Antala; Ahmed Abdulrahman; Valiko Begiashvili; Khalid Mohamed; Elrazi Ali; Qishou Zhang
Journal:  J Med Cases       Date:  2022-09-28

2.  Polyarthritis and Psoriasiform Skin Lesions following Pembrolizumab Therapy.

Authors:  Vasiliki Koulouri; Michalis V Karamouzis; Clio P Mavragani
Journal:  Mediterr J Rheumatol       Date:  2021-12-27

3.  Vitiligo-specific soluble biomarkers as early indicators of response to immune checkpoint inhibitors in metastatic melanoma patients.

Authors:  Elisabetta Volpe; Cristina Maria Failla; Maria Luigia Carbone; Gabriele Madonna; Alessia Capone; Marianna Bove; Simona Mastroeni; Lauretta Levati; Mariaelena Capone; Paolo Antonio Ascierto; Federica De Galitiis; Stefania D'Atri; Cristina Fortes
Journal:  Sci Rep       Date:  2022-03-31       Impact factor: 4.996

4.  Clinical Retrospective Analysis of 243 Patients with Rhinofacial Ulcers.

Authors:  Weiyuan Ma; Ruyu Zhan; Changlin Sui; Fushan Zhou; Haidong Liu; Xiuwen Zhang; Zhenqiang Ruan; Yukun Wang; Xiaolan Cai
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-08-01
  4 in total

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