Literature DB >> 32317329

AKI!Now Initiative: Recommendations for Awareness, Recognition, and Management of AKI.

Kathleen D Liu1, Stuart L Goldstein2, Anitha Vijayan3, Chirag R Parikh4, Kianoush Kashani5, Mark D Okusa6, Anupam Agarwal7, Jorge Cerdá8.   

Abstract

The American Society of Nephrology has established a new initiative, AKI!Now, with the goal of promoting excellence in the prevention and treatment of AKI by building a foundational program that transforms education and delivery of AKI care, aiming to reduce morbidity and associated mortality and to improve long-term outcomes. In this article, we describe our current efforts to improve early recognition and management involving inclusive interdisciplinary collaboration between providers, patients, and their families; discuss the ongoing need to change some of our current AKI paradigms and diagnostic methods; and provide specific recommendations to improve AKI recognition and care. In the hospital and the community, AKI is a common and increasingly frequent condition that generates risks of adverse events and high costs. Unfortunately, patients with AKI may frequently have received less than optimal quality of care. New classifications have facilitated understanding of AKI incidence and its impact on outcomes, but they are not always well aligned with AKI pathophysiology. Despite ongoing research efforts, treatments to promote or hasten kidney recovery remain ineffective. To avoid progression, the current approach to AKI emphasizes the promotion of early recognition and timely response. However, a lack of awareness of the importance of early recognition and treatment among health care team members and the heterogeneity of approaches within the health care teams assessing the patient remains a major challenge. Early identification is further complicated by differences in settings where AKI occurs (the community or the hospital), and by differences in patient populations and cultures between the intensive care unit and ward environments. To address these obstacles, we discuss the need to improve education at all levels of care and to generate specific guidance on AKI evaluation and management, including the development of a widely applicable education and an AKI management toolkit, engaging hospital administrators to incorporate AKI as a quality initiative, and raising awareness of AKI as a complication of other disease processes.
Copyright © 2020 by the American Society of Nephrology.

Entities:  

Keywords:  AKI awareness; AKI biomarkers; AKI multidisciplinary management; AKI pathology; AKI recognition; AKI urinalysis; acute kidney injury; artificial intelligence; critical care nephrology; electronic alerts; goals; hospital administrators; incidence; intensive care units; kidney; longitudinal studies; morbidity; patient care team; quality of health care

Mesh:

Year:  2020        PMID: 32317329      PMCID: PMC7769012          DOI: 10.2215/CJN.15611219

Source DB:  PubMed          Journal:  Clin J Am Soc Nephrol        ISSN: 1555-9041            Impact factor:   8.237


  86 in total

1.  Automated, electronic alerts for acute kidney injury: a single-blind, parallel-group, randomised controlled trial.

Authors:  F Perry Wilson; Michael Shashaty; Jeffrey Testani; Iram Aqeel; Yuliya Borovskiy; Susan S Ellenberg; Harold I Feldman; Hilda Fernandez; Yevgeniy Gitelman; Jennie Lin; Dan Negoianu; Chirag R Parikh; Peter P Reese; Richard Urbani; Barry Fuchs
Journal:  Lancet       Date:  2015-02-26       Impact factor: 79.321

Review 2.  Critical care nephrology: the time has come.

Authors:  C Ronco; R Bellomo
Journal:  Nephrol Dial Transplant       Date:  1998-02       Impact factor: 5.992

Review 3.  International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology.

Authors:  Ravindra L Mehta; Jorge Cerdá; Emmanuel A Burdmann; Marcello Tonelli; Guillermo García-García; Vivekanand Jha; Paweena Susantitaphong; Michael Rocco; Raymond Vanholder; Mehmet Sukru Sever; Dinna Cruz; Bertrand Jaber; Norbert H Lameire; Raúl Lombardi; Andrew Lewington; John Feehally; Fredric Finkelstein; Nathan Levin; Neesh Pannu; Bernadette Thomas; Eliah Aronoff-Spencer; Giuseppe Remuzzi
Journal:  Lancet       Date:  2015-03-13       Impact factor: 79.321

4.  Assessment of a renal angina index for prediction of severe acute kidney injury in critically ill children: a multicentre, multinational, prospective observational study.

Authors:  Rajit K Basu; Ahmad Kaddourah; Stuart L Goldstein
Journal:  Lancet Child Adolesc Health       Date:  2018-02

5.  Simple Postoperative AKI Risk (SPARK) Classification before Noncardiac Surgery: A Prediction Index Development Study with External Validation.

Authors:  Sehoon Park; Hyunjeong Cho; Seokwoo Park; Soojin Lee; Kwangsoo Kim; Hyung Jin Yoon; Jiwon Park; Yunhee Choi; Suehyun Lee; Ju Han Kim; Sejoong Kim; Ho Jun Chin; Dong Ki Kim; Kwon Wook Joo; Yon Su Kim; Hajeong Lee
Journal:  J Am Soc Nephrol       Date:  2018-12-18       Impact factor: 10.121

6.  Risk Factor Analysis for AKI Including Laboratory Indicators: a Nationwide Multicenter Study of Hospitalized Patients.

Authors:  Sasa Nie; Zhe Feng; Li Tang; Xiaolong Wang; Yani He; Jingai Fang; Suhua Li; Yibin Yang; Huijuan Mao; Jundong Jiao; Wenhu Liu; Ning Cao; Wenge Wang; Jifeng Sun; Fengmin Shao; Wenge Li; Qiang He; Hongli Jiang; Hongli Lin; Ping Fu; Xinzhou Zhang; Yinghong Liu; Yonggui Wu; ChunSheng Xi; Meng Liang; Zhijie Qu; Jun Zhu; Guangli Wu; Yali Zheng; Yu Na; Ying Li; Wei Li; Guangyan Cai; Xiangmei Chen
Journal:  Kidney Blood Press Res       Date:  2017-10-24       Impact factor: 2.687

7.  Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular Injury.

Authors:  Dennis G Moledina; Isaac E Hall; Heather Thiessen-Philbrook; Peter P Reese; Francis L Weng; Bernd Schröppel; Mona D Doshi; F Perry Wilson; Steven G Coca; Chirag R Parikh
Journal:  Am J Kidney Dis       Date:  2017-08-24       Impact factor: 8.860

8.  Biomarker validation with an imperfect reference: Issues and bounds.

Authors:  Sarah C Emerson; Sushrut S Waikar; Claudio Fuentes; Joseph V Bonventre; Rebecca A Betensky
Journal:  Stat Methods Med Res       Date:  2017-02-06       Impact factor: 3.021

9.  A clinical score to predict acute renal failure after cardiac surgery.

Authors:  Charuhas V Thakar; Susana Arrigain; Sarah Worley; Jean-Pierre Yared; Emil P Paganini
Journal:  J Am Soc Nephrol       Date:  2004-11-24       Impact factor: 10.121

10.  A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation.

Authors:  Roxana Mehran; Eve D Aymong; Eugenia Nikolsky; Zoran Lasic; Ioannis Iakovou; Martin Fahy; Gary S Mintz; Alexandra J Lansky; Jeffrey W Moses; Gregg W Stone; Martin B Leon; George Dangas
Journal:  J Am Coll Cardiol       Date:  2004-10-06       Impact factor: 24.094

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  19 in total

Review 1.  The Intersection of Acute Kidney Injury and Non-Coding RNAs: Inflammation.

Authors:  Bojun Li; Fangyou Lin; Yuqi Xia; Zehua Ye; Xinzhou Yan; Baofeng Song; Tianhui Yuan; Lei Li; Xiangjun Zhou; Weimin Yu; Fan Cheng
Journal:  Front Physiol       Date:  2022-06-09       Impact factor: 4.755

Review 2.  Overview of Diagnostic Criteria and Epidemiology of Acute Kidney Injury and Acute Kidney Disease in the Critically Ill Patient.

Authors:  Bethany C Birkelo; Neesh Pannu; Edward D Siew
Journal:  Clin J Am Soc Nephrol       Date:  2022-03-15       Impact factor: 10.614

3.  Artificial Intelligence for AKI!Now: Let's Not Await Plato's Utopian Republic.

Authors:  Danielle E Soranno; Azra Bihorac; Stuart L Goldstein; Kianoush B Kashani; Shina Menon; Girish N Nadkarni; Javier A Neyra; Neesh I Pannu; Karandeep Singh; Jorge Cerda; Jay L Koyner
Journal:  Kidney360       Date:  2021-11-18

4.  The importance of early detecting high-risk patients with acute kidney injury requiring continuous kidney replacement therapy.

Authors:  Antonietta Gigante; Francesca Di Mario; Stefania Basili
Journal:  Intern Emerg Med       Date:  2022-10-22       Impact factor: 5.472

5.  Restoration of afferent arteriolar autoregulatory behavior in ischemia-reperfusion injury in rat kidneys.

Authors:  Wenguang Feng; Colton E Remedies; Ijeoma E Obi; Stephen R Aldous; Samia I Meera; Paul W Sanders; Edward W Inscho; Zhengrong Guan
Journal:  Am J Physiol Renal Physiol       Date:  2021-01-25

Review 6.  The use of diagnostic tools for pediatric AKI: applying the current evidence to the bedside.

Authors:  Dana Fuhrman
Journal:  Pediatr Nephrol       Date:  2021-01-25       Impact factor: 3.714

Review 7.  Sustainable Development Goals relevant to kidney health: an update on progress.

Authors:  Valerie A Luyckx; Ziyad Al-Aly; Aminu K Bello; Ezequiel Bellorin-Font; Raul G Carlini; June Fabian; Guillermo Garcia-Garcia; Arpana Iyengar; Mohammed Sekkarie; Wim van Biesen; Ifeoma Ulasi; Karen Yeates; John Stanifer
Journal:  Nat Rev Nephrol       Date:  2020-11-13       Impact factor: 28.314

8.  Dynamic R2' Imaging can Be a Biomarker for Diagnosing and Staging Early Acute Kidney Injury in Animals.

Authors:  Bihui Zhang; Ziping Yao; Weizheng Gao; Chengyan Wang; Hanjing Kong; Jue Zhang; Min Yang
Journal:  Front Med (Lausanne)       Date:  2021-12-24

9.  Health Care Analytics With Time-Invariant and Time-Variant Feature Importance to Predict Hospital-Acquired Acute Kidney Injury: Observational Longitudinal Study.

Authors:  Horng-Ruey Chua; Kaiping Zheng; Anantharaman Vathsala; Kee-Yuan Ngiam; Hui-Kim Yap; Liangjian Lu; Ho-Yee Tiong; Amartya Mukhopadhyay; Graeme MacLaren; Shir-Lynn Lim; K Akalya; Beng-Chin Ooi
Journal:  J Med Internet Res       Date:  2021-12-24       Impact factor: 5.428

10.  Postoperative complications of endovascular blunt thoracic aortic injury repair.

Authors:  Hossam Abdou; Noha N Elansary; Louisa Darko; Joseph J DuBose; Thomas M Scalea; Jonathan J Morrison; Rishi Kundi
Journal:  Trauma Surg Acute Care Open       Date:  2021-07-15
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