Literature DB >> 32317289

Improving AML Classification Using Splicing Signatures.

Teresa V Bowman1.   

Abstract

Mutations in spliceosomal components are prevalent in myelodysplastic syndromes, but less so in acute myeloid leukemia (AML). However, aberrant splicing is prolific in AML, suggesting deregulated splicing could contribute broadly to tumorigenesis. Elevated stress responses correlate with splicing dysfunction across myeloid malignancies, representing potentially novel therapeutic targets.See related article by Anande et al., p. 3597. ©2020 American Association for Cancer Research.

Entities:  

Mesh：

Year:  2020        PMID： 32317289      PMCID： PMC7367749          DOI： 10.1158/1078-0432.CCR-20-1021

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  5 in total

Review 1.  Splicing factor mutant myelodysplastic syndromes: Recent advances.

Authors:  Andrea Pellagatti; Jacqueline Boultwood
Journal:  Adv Biol Regul       Date:  2019-09-19

2.  RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia.

Authors:  Ashwin Unnikrishnan; John E Pimanda; Govardhan Anande; Nandan P Deshpande; Sylvain Mareschal; Aarif M N Batcha; Henry R Hampton; Tobias Herold; Soren Lehmann; Marc R Wilkins; Jason W H Wong
Journal:  Clin Cancer Res       Date:  2020-03-02       Impact factor: 12.531

Review 3.  RNA-binding proteins in hematopoiesis and hematological malignancy.

Authors:  Daniel J Hodson; Michael Screen; Martin Turner
Journal:  Blood       Date:  2019-04-09       Impact factor: 22.113

Review 4.  Emerging therapies for acute myeloid leukemia.

Authors:  Caner Saygin; Hetty E Carraway
Journal:  J Hematol Oncol       Date:  2017-04-18       Impact factor: 17.388

5.  Functional genomic landscape of acute myeloid leukaemia.

Authors:  Jeffrey W Tyner; Cristina E Tognon; Daniel Bottomly; Beth Wilmot; Stephen E Kurtz; Samantha L Savage; Nicola Long; Anna Reister Schultz; Elie Traer; Melissa Abel; Anupriya Agarwal; Aurora Blucher; Uma Borate; Jade Bryant; Russell Burke; Amy Carlos; Richie Carpenter; Joseph Carroll; Bill H Chang; Cody Coblentz; Amanda d'Almeida; Rachel Cook; Alexey Danilov; Kim-Hien T Dao; Michie Degnin; Deirdre Devine; James Dibb; David K Edwards; Christopher A Eide; Isabel English; Jason Glover; Rachel Henson; Hibery Ho; Abdusebur Jemal; Kara Johnson; Ryan Johnson; Brian Junio; Andy Kaempf; Jessica Leonard; Chenwei Lin; Selina Qiuying Liu; Pierrette Lo; Marc M Loriaux; Samuel Luty; Tara Macey; Jason MacManiman; Jacqueline Martinez; Motomi Mori; Dylan Nelson; Ceilidh Nichols; Jill Peters; Justin Ramsdill; Angela Rofelty; Robert Schuff; Robert Searles; Erik Segerdell; Rebecca L Smith; Stephen E Spurgeon; Tyler Sweeney; Aashis Thapa; Corinne Visser; Jake Wagner; Kevin Watanabe-Smith; Kristen Werth; Joelle Wolf; Libbey White; Amy Yates; Haijiao Zhang; Christopher R Cogle; Robert H Collins; Denise C Connolly; Michael W Deininger; Leylah Drusbosky; Christopher S Hourigan; Craig T Jordan; Patricia Kropf; Tara L Lin; Micaela E Martinez; Bruno C Medeiros; Rachel R Pallapati; Daniel A Pollyea; Ronan T Swords; Justin M Watts; Scott J Weir; David L Wiest; Ryan M Winters; Shannon K McWeeney; Brian J Druker
Journal:  Nature       Date:  2018-10-17       Impact factor: 49.962
  5 in total
  1 in total

1.  Explainable artificial intelligence for precision medicine in acute myeloid leukemia.

Authors:  Marian Gimeno; Edurne San José-Enériz; Sara Villar; Xabier Agirre; Felipe Prosper; Angel Rubio; Fernando Carazo
Journal:  Front Immunol       Date:  2022-09-29       Impact factor: 8.786
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.