| Literature DB >> 32314547 |
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Abstract
Entities:
Year: 2020 PMID: 32314547 PMCID: PMC7171340 DOI: 10.1111/jcmm.15085
Source DB: PubMed Journal: J Cell Mol Med ISSN: 1582-1838 Impact factor: 5.310
Figure 2LINC01133 knockdown promotes breast cancer cells migration, invasion and viability in vitro. A, qRT‐PCR analysis of LINC01133 expression in normal breast epithelial cell line (MCF‐10A) and human breast cancer cells. B, Relative expression of LINC01133 in MDA‐MB‐231 and MCF‐7 cells after transfecting with LINC01133 shRNA compared with negative control (Nc). C, D, Wound‐healing assays were performed to assess cell migration following LINC01133 knockdown or Nc in MDA‐MB‐231 and MCF‐7 cells. E, Transwell assays were performed to evaluate cell invasion following LINCO1133 knockdown or Nc in MDA‐MB‐231 and MCF‐7 cells. F, G, CCK‐8 assay of LINC01133 knockdown (shRNAs) and NC breast cancer cells at indicated times
Figure 3LINC01133 overexpression suppresses breast cancer cells migration, invasion and viability in vitro. A, Relative expression of LINC01133 in MDA‐MB‐231 and MCF‐7 cells transfecting with vector for LINC01133 overexpression compared with vector Nc. B, C, Wound‐healing assays were performed to assess cell migration following LINC01133 overexpression or Nc in MDA‐MB‐231 and MCF‐7 cells. D, Transwell assays were performed to evaluate cell invasion following LINCO1133 overexpression or NC in MDA‐MB‐231 and MCF‐7 cells. E, F, CCK‐8 assay of LINC01133 overexpression and NC breast cancer cells at indicated times